Protein Kinase Inhibitor, Staurosporine, Prevents Okadaic Acid- or Caffeine-induced Chromosome Condensation

Overview

Journal In Vitro Cell Dev Biol Anim

Publisher Springer

Specialties Biology
Cell Biology

Date 1993 Oct 1

PMID 8118609

Authors

K Nakamura

S Antoku

Affiliations

Soon will be listed here.

References

Nurse P . Universal control mechanism regulating onset of M-phase. Nature. 1990; 344(6266):503-8. DOI: 10.1038/344503a0. View

Yamashita K, Yasuda H, Pines J, Yasumoto K, Nishitani H, Ohtsubo M . Okadaic acid, a potent inhibitor of type 1 and type 2A protein phosphatases, activates cdc2/H1 kinase and transiently induces a premature mitosis-like state in BHK21 cells. EMBO J. 1990; 9(13):4331-8. PMC: 552219. DOI: 10.1002/j.1460-2075.1990.tb07882.x. View

Schlegel R, Belinsky G, Harris M . Premature mitosis induced in mammalian cells by the protein kinase inhibitors 2-aminopurine and 6-dimethylaminopurine. Cell Growth Differ. 1990; 1(4):171-8. View

Abe K, Yoshida M, Usui T, Horinouchi S, Beppu T . Highly synchronous culture of fibroblasts from G2 block caused by staurosporine, a potent inhibitor of protein kinases. Exp Cell Res. 1991; 192(1):122-7. DOI: 10.1016/0014-4827(91)90166-r. View

Norbury C, Nurse P . Control of the higher eukaryote cell cycle by p34cdc2 homologues. Biochim Biophys Acta. 1989; 989(1):85-95. DOI: 10.1016/0304-419x(89)90036-x. View

Nicolini C, Ajiro K, Borun T, Baserga R . Chromatin changes during the cell cycle of HeHa cells. J Biol Chem. 1975; 250(9):3381-5. View

Farrell P, Balkow K, Hunt T, Jackson R, Trachsel H . Phosphorylation of initiation factor elF-2 and the control of reticulocyte protein synthesis. Cell. 1977; 11(1):187-200. DOI: 10.1016/0092-8674(77)90330-0. View

Schlegel R, Pardee A . Caffeine-induced uncoupling of mitosis from the completion of DNA replication in mammalian cells. Science. 1986; 232(4755):1264-6. DOI: 10.1126/science.2422760. View

Nishimoto T, Eilen E, Basilico C . Premature of chromosome condensation in a ts DNA- mutant of BHK cells. Cell. 1978; 15(2):475-83. DOI: 10.1016/0092-8674(78)90017-x. View

10.

Nakamura K, Antoku S . Staurosporine induces multinucleation following chromosome decondensation in Colcemid-arrested cells. In Vitro Cell Dev Biol Anim. 1993; 29A(7):525-7. DOI: 10.1007/BF02634144. View

11.

Pines J, Hunter T . p34cdc2: the S and M kinase?. New Biol. 1990; 2(5):389-401. View

12.

Dolby T, Ajiro K, Borun T, Gilmour R, Zweidler A, Cohen L . Physical properties of DNA and chromatin isolated from G1- and S-phase HeLa S-3 cells. Effects of histone H1 phosphorylation and stage-specific nonhistone chromosomal proteins on the molar ellipticity of native and reconstituted nucleoproteins.... Biochemistry. 1979; 18(7):1333-44. DOI: 10.1021/bi00574a033. View