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PCR Amplification of Variable Sequence Upstream of KatG Gene to Subdivide Strains of Mycobacterium Tuberculosis Complex

Overview
Specialty Microbiology
Date 1994 Dec 1
PMID 7883905
Citations 13
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Abstract

PCR amplification of a species-specific 2-kb KpnI fragment of variable size located 10 kb upstream of the katG gene was used to subdivide 130 clinical isolates of Mycobacterium tuberculosis. Seven subtypes were identified, and their frequencies were distributed normally with respect to the size of the amplified product.

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