Alpha 2.0
Login Register
» Articles » PMID: 7860211

Serum Immunosuppressive Acidic Protein in Haemodialysis Patients with and Without Acquired Cystic Disease of the Kidney

Overview
Journal Int Urol Nephrol
Publisher Springer
Specialty Nephrology
Date 1994 Jan 1
PMID 7860211
Authors
I Sasagawa
T Nakada
Y Kubota
T Sawamura
Affiliations
Soon will be listed here.
Abstract

Serum levels of immunosuppressive acidic protein (IAP) were measured in 20 haemodialysis patients with acquired cystic disease of the kidney (ACDK) and in 44 without it. Serum IAP levels in haemodialysis patients with and without ACDK were significantly elevated compared to that in controls. However, there was no considerable difference between haemodialysis patients with and without ACDK. A significant reduction in this marker was not found after dialysis treatment. This indicates that elevation of IAP may be related to an increased incidence of renal cell carcinoma in haemodialysis patients.

References
1.
Tamura K, Shibata Y, Matsuda Y, Ishida N . Isolation and characterization of an immunosuppressive acidic protein from ascitic fluids of cancer patients. Cancer Res. 1981; 41(8):3244-52. View
2.
Herrera G . C-erb B-2 amplification in cystic renal disease. Kidney Int. 1991; 40(3):509-13. DOI: 10.1038/ki.1991.239. View
3.
Lee C, MAUER S, Brown D, Sutherland D, Michael A, Najarian J . Renal transplantation in diabetes mellitus in rats. J Exp Med. 1974; 139(4):793-800. PMC: 2139572. DOI: 10.1084/jem.139.4.793. View
4.
Dunnill M, Millard P, Oliver D . Acquired cystic disease of the kidneys: a hazard of long-term intermittent maintenance haemodialysis. J Clin Pathol. 1977; 30(9):868-77. PMC: 476578. DOI: 10.1136/jcp.30.9.868. View
5.
Ueda T . Serum immunosuppressive acidic protein in renal cell carcinoma. Urol Res. 1986; 14(2):101-3. DOI: 10.1007/BF00257894. View