» Articles » PMID: 3727211

Serum Immunosuppressive Acidic Protein in Renal Cell Carcinoma

Overview
Journal Urol Res
Specialty Urology
Date 1986 Jan 1
PMID 3727211
Citations 1
Authors
Affiliations
Soon will be listed here.
Abstract

Serum immunosuppressive acidic protein (IAP) was determined in 45 patients with renal cell carcinoma (20 preoperative and 25 postoperative) and 12 healthy adults. The mean values of serum IAP in patients with renal cell carcinoma of low stage (566.3 +/- 197.7 micrograms/ml) and high stage (936.9 +/- 208.8 micrograms/ml) were statistically higher than those of controls (368.8 +/- 84.5 micrograms/ml). Positive rate of IAP levels was found in 58.3% and 100% of patients with low stage and high stage, respectively. The mean value of serum IAP was 756.4 +/- 361.0 micrograms/ml in patients with metastases, while patients without metastases had a value of 434.7 +/- 170.9 micrograms/ml. There was a statistically significant difference between the two populations. These results suggest that IAP levels appear to provide a useful diagnostic and follow-up marker in renal cell carcinoma patients.

Citing Articles

Serum immunosuppressive acidic protein in haemodialysis patients with and without acquired cystic disease of the kidney.

Sasagawa I, Nakada T, Kubota Y, Sawamura T Int Urol Nephrol. 1994; 26(5):595-8.

PMID: 7860211 DOI: 10.1007/BF02767665.

References
1.
Shimizu Y, Oshima K, Nakano Y, Fujita M, Taguchi T . Significance of pregnancy-associated alpha 2-glycoprotein (alpha 2-PAG) in patients with breast, gastric and colorectal cancer. Biken J. 1981; 24(3):95-102. View

2.
Tamura K, Shibata Y, Matsuda Y, Ishida N . Isolation and characterization of an immunosuppressive acidic protein from ascitic fluids of cancer patients. Cancer Res. 1981; 41(8):3244-52. View

3.
Javadpour N . Tumor markers in urologic cancer. Urology. 1980; 16(2):127-36. DOI: 10.1016/0090-4295(80)90065-5. View

4.
Sawada M, Okudaira Y, Matsui Y, Shimizu Y . Immunosuppressive acidic protein in patients with ovarian cancer. Cancer. 1983; 52(11):2081-5. DOI: 10.1002/1097-0142(19831201)52:11<2081::aid-cncr2820521119>3.0.co;2-t. View

5.
ROBSON C, Churchill B, Anderson W . The results of radical nephrectomy for renal cell carcinoma. J Urol. 1969; 101(3):297-301. DOI: 10.1016/s0022-5347(17)62331-0. View