Epidemiology of Tetracycline-resistance Determinants

Overview

Journal Trends Microbiol

Date 1994 Oct 1

PMID 7850200

Citations 39

Authors

M C Roberts

Affiliations

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Abstract

Resistance to tetracycline is generally due either to energy-dependent efflux of tetracycline or to protection of the bacterial ribosomes from the action of tetracycline. The genes that encode this resistance are normally acquired via transferable plasmids and/or transposons. Tet determinants have been found in a wide range of Gram-positive and Gram-negative bacteria and have reduced the effectiveness of therapy with tetracycline.

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