Periodontitis Disease in Farmed Ruminants-Current State of Research

Overview

Journal Int J Mol Sci

Publisher MDPI

Specialties Biochemistry
Chemistry
Molecular Biology

Date 2023 Jun 10

PMID 37298712

Authors

Arkadiusz Grzeczka

Marianna Lech

Gracjan Wozniak

Szymon Graczyk

Pawel Kordowitzki

Malgorzata Olejnik

Marek Gehrke

Jedrzej Maria Jaskowski

Affiliations

Soon will be listed here.

Abstract

Periodontal disease in ruminants is common and occurs in farmed and wild animals. Periodontal lesions can result from the secretion of endotoxins by pathogenic bacteria and as consequences of immune system activity. Three main types of periodontitis have been described. The first is chronic inflammation involving mainly premolars and molars-periodontitis (PD). The second type is an acute inflammatory reaction occurring with calcification of the periosteum of the jawbone and swelling of the surrounding soft tissues (Cara inchada, CI-"swollen face"). Finally, a third type, similar to the first but located in the incisor area, is called "broken mouth" (BM). Etiological variation between the different types of periodontitis is indicated. This particularly manifests in the composition of the microbiome, which is characteristic of the different forms of periodontitis. The widespread detection of lesions has drawn attention to the current nature of the problem.

Citing Articles

Characterization of the Hoof Bacterial Communities of Active Digital Dermatitis Lesions in Feedlot Cattle.

Wong N, Malmuthuge N, Gellatly D, Nordi W, Alexander T, Ortega-Polo R Microorganisms. 2024; 12(7).

PMID: 39065237 PMC: 11278616. DOI: 10.3390/microorganisms12071470.

O-Linked N-Acetylglucosamine Transferase Regulates Bone Homeostasis Through Alkaline Phosphatase Pathway in Diabetic Periodontitis.

Luo W, Sun L Mol Biotechnol. 2023; 66(12):3475-3484.

PMID: 37951846 DOI: 10.1007/s12033-023-00947-0.

Effects of N-acetyl-L-cysteine polysulfides on periodontitis in a mouse model.

Sun X, Sun Y, Cao S, Liu X Immun Inflamm Dis. 2023; 11(8):e959.

PMID: 37647428 PMC: 10408371. DOI: 10.1002/iid3.959.

References

Seymour R, Heasman P . Tetracyclines in the management of periodontal diseases. A review. J Clin Periodontol. 1995; 22(1):22-35. DOI: 10.1111/j.1600-051x.1995.tb01767.x. View

Kesavalu L, Chandrasekar B, Ebersole J . In vivo induction of proinflammatory cytokines in mouse tissue by Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans. Oral Microbiol Immunol. 2002; 17(3):177-80. DOI: 10.1034/j.1399-302x.2002.170307.x. View

Sanavi F, Zander H, Rifkin B . The effect of indomethacin on alveolar bone loss in experimental periodontitis. J Periodontal Res. 1982; 17(1):90-100. DOI: 10.1111/j.1600-0765.1982.tb01134.x. View

Larsen G, Henson P . Mediators of inflammation. Annu Rev Immunol. 1983; 1:335-59. DOI: 10.1146/annurev.iy.01.040183.002003. View

Borsanelli A, Lappin D, Viora L, King G, Bennett D, Dutra I . Evaluation of tissue levels of Toll-like receptors and cytokine mRNAs associated with bovine periodontitis and oral health. Res Vet Sci. 2018; 118:439-443. DOI: 10.1016/j.rvsc.2018.04.008. View

Senhorinho G, Nakano V, Liu C, Song Y, Finegold S, Avila-Campos M . Occurrence and antimicrobial susceptibility of Porphyromonas spp. and Fusobacterium spp. in dogs with and without periodontitis. Anaerobe. 2012; 18(4):381-5. DOI: 10.1016/j.anaerobe.2012.04.008. View

Stashenko P, Fujiyoshi P, Obernesser M, Prostak L, Haffajee A, Socransky S . Levels of interleukin 1 beta in tissue from sites of active periodontal disease. J Clin Periodontol. 1991; 18(7):548-54. DOI: 10.1111/j.1600-051x.1991.tb00088.x. View

Spence J, Aitchison G, Sykes A, Atkinson P . Broken mouth (premature incisor loss) in sheep: the pathogenesis of periodontal disease. J Comp Pathol. 1980; 90(2):275-92. DOI: 10.1016/0021-9975(80)90064-x. View

Lindhe J, Berglundh T, Ericsson I, Liljenberg B, Marinello C . Experimental breakdown of peri-implant and periodontal tissues. A study in the beagle dog. Clin Oral Implants Res. 1992; 3(1):9-16. DOI: 10.1034/j.1600-0501.1992.030102.x. View

10.

Borsanelli A, Athayde F, Saraiva J, Riggio M, Dutra I . Dysbiosis and Predicted Functions of the Dental Biofilm of Dairy Goats with Periodontitis. Microb Ecol. 2022; 86(1):687-698. DOI: 10.1007/s00248-022-02062-0. View

11.

Holmes M, Thomas R, Hamerow H . Identifying draught cattle in the past: Lessons from large-scale analysis of archaeological datasets. Int J Paleopathol. 2021; 33:258-269. DOI: 10.1016/j.ijpp.2021.05.004. View

12.

Borsanelli A, Lappin D, Viora L, Bennett D, Dutra I, Brandt B . Microbiomes associated with bovine periodontitis and oral health. Vet Microbiol. 2018; 218:1-6. DOI: 10.1016/j.vetmic.2018.03.016. View

13.

HARVEY C . Periodontal disease in dogs. Etiopathogenesis, prevalence, and significance. Vet Clin North Am Small Anim Pract. 1998; 28(5):1111-28, vi. DOI: 10.1016/s0195-5616(98)50105-2. View

14.

Sturgeon A, Pinder S, Costa M, Weese J . Characterization of the oral microbiota of healthy cats using next-generation sequencing. Vet J. 2014; 201(2):223-9. DOI: 10.1016/j.tvjl.2014.01.024. View

15.

Heft M, Perelmuter S, Cooper B, Magnusson I, Clark W . Relationship between gingival inflammation and painfulness of periodontal probing. J Clin Periodontol. 1991; 18(3):213-5. DOI: 10.1111/j.1600-051x.1991.tb01137.x. View

16.

Lund E, Armstrong P, Kirk C, Kolar L, Klausner J . Health status and population characteristics of dogs and cats examined at private veterinary practices in the United States. J Am Vet Med Assoc. 1999; 214(9):1336-41. View

17.

Cafferata E, Terraza-Aguirre C, Barrera R, Faundez N, Gonzalez N, Rojas C . Interleukin-35 inhibits alveolar bone resorption by modulating the Th17/Treg imbalance during periodontitis. J Clin Periodontol. 2020; 47(6):676-688. DOI: 10.1111/jcpe.13282. View

18.

Borsanelli A, Viora L, Parkin T, Lappin D, Bennett D, King G . Risk factors for bovine periodontal disease - a preliminary study. Animal. 2021; 15(2):100121. DOI: 10.1016/j.animal.2020.100121. View

19.

Tanaka S, Yoshida M, Murakami Y, Ogiwara T, Shoji M, Kobayashi S . The relationship of Prevotella intermedia, Prevotella nigrescens and Prevotella melaninogenica in the supragingival plaque of children, caries and oral malodor. J Clin Pediatr Dent. 2008; 32(3):195-200. DOI: 10.17796/jcpd.32.3.vp657177815618l1. View

20.

Shore R, Moxham B, Berkovitz B . Effects of inflammatory periodontal disease ('broken mouth') on the ultrastructure of collagen fibrils in the sheep incisor periodontium. Res Vet Sci. 1989; 47(2):148-51. View