Case Report: Congenital Adrenal Hyperplasia and Malignant Leydig Cell Tumor

Overview

Journal Am J Med Sci

Publisher Elsevier

Specialty General Medicine

Date 1995 Jan 1

PMID 7825657

Citations 6

Authors

J M Davis

J Woodroof

R Sadasivan

R Stephens

Affiliations

Soon will be listed here.

Abstract

Leydig cell tumors are very rarely seen testicular tumors and can be difficult to distinguish from testicular tumors of the adrenogenital syndrome. Testicular tumors of the adrenogenital syndrome are confined to patients with congenital adrenal hyperplasia. The authors report a case of a patient with malignant Leydig cell tumor and a history of congenital adrenal hyperplasia (adrenogenital syndrome). To the authors' knowledge, this has not been reported previously.

Citing Articles

GATA transcription factors in testicular adrenal rest tumours.

Engels M, Span P, Mitchell R, Heuvel J, Marijnissen-van Zanten M, van Herwaarden A Endocr Connect. 2017; 6(8):866-875.

PMID: 29038332 PMC: 5682415. DOI: 10.1530/EC-17-0215.

[Leydig cell, Sertoli cell and adult granulosa cell tumors].

Bremmer F, Schweyer S Pathologe. 2016; 37(1):71-7.

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[Sex cord gonadal stromal tumors].

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Two novel mutations in CYP11B1 and modeling the consequent alterations of the translated protein in classic congenital adrenal hyperplasia patients.

Abbaszadegan M, Hassani S, Vakili R, Saberi M, Baradaran-Heravi A, Arabi A Endocrine. 2013; 44(1):212-9.

PMID: 23345044 DOI: 10.1007/s12020-012-9861-2.

Leydig Cell Tumor Associated with Testicular Adrenal Rest Tumors in a Patient with Congenital Adrenal Hyperplasia due to 11β-Hydroxylase Deficiency.

Charfi N, Kamoun M, Mnif M, Mseddi N, Mnif F, Kallel N Case Rep Urol. 2012; 2012:648643.

PMID: 22606635 PMC: 3350130. DOI: 10.1155/2012/648643.