Antibiotic Resistance and Penicillin Tolerance in Clinical Isolates of Group B Streptococci

Overview

Journal Antimicrob Agents Chemother

Publisher American Society for Microbiology

Specialty Pharmacology

Date 1994 Sep 1

PMID 7811042

Citations 21

Authors

C Betriu

M Gomez

A Sanchez

A Cruceyra

J Romero

J J Picazo

Affiliations

Soon will be listed here.

Abstract

The aim of this study was to determine the susceptibility patterns of 100 group B streptococcal strains isolated in our hospital and to ascertain tolerance to penicillin by determining quantitative killing curves. We found two strains with intermediate susceptibility to penicillin and eight strains to ampicillin. Seventeen isolates were tolerant to penicillin, with bacterial counts decreasing 2 to 3 log during the first 8 h but still above 10(2) CFU/ml after 24 h. The kinetic study shows that penicillin tolerance is not rare among group B streptococci isolated in our hospital.

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