Comparison Between Metacarpal Bone Measurements by Computarized Radiogrammetry and Total Body DEXA in Normal and Osteoporotic Women

Overview

Journal Clin Rheumatol

Publisher Springer

Specialty Rheumatology

Date 1994 Dec 1

PMID 7697961

Citations 4

Authors

H Rico

M Revilla

L F Villa

J L Cardenas

E Fraile

Affiliations

Soon will be listed here.

Abstract

We evaluated the precision of metacarpal radiogrammetry by computed radiography as a technique for bone mass measurement. Measurements obtained using this method were compared with densitometric measurements of total body bone mass using dual-energy X-ray absorptiometry. Our results showed that the coefficients of variation for radiogrammetric measurements were similar in 60 women with osteoporosis and in 100 normal women: 0.7% in both groups for external diameter of the second metacarpal, 2.41% in the normal women and 2.03% in the women with osteoporosis for internal diameter, and 2.3% and 2.4%, respectively, for cortical thickness. Except for external metacarpal diameter, which did not differ between normal and osteoporotic women, all the measurements were smaller in the women with osteoporosis (p < 0.001). The correlation between metacarpal cortical thickness and total body bone mineral content was r2 = 0.462 in the women with osteoporosis, r2 = 0.476 in the controls, and r2 = 0.522 in the two groups combined (all p < 0.001). There was a significant correlation (p < 0.001) between cortical thickness and densitometric metacarpal measurements of both the diaphysis and epiphysis. These results confirm the value of radiogrammetry as a technique for quantitating bone mass under normal and pathological conditions. Additional advantages of the method are minimal radiation dose delivered, possibility for storing the image and data, and technical facility.

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References

Moore R, Durbridge T, McNeil P, Parkinson I, Need A, Vernon-Roberts B . Trabecular spacing in post-menopausal Australian women with and without vertebral fractures. Aust N Z J Med. 1992; 22(3):269-73. DOI: 10.1111/j.1445-5994.1992.tb02124.x. View

Elders P, Habets L, Netelenbos J, van der Linden L, van der Stelt P . The relation between periodontitis and systemic bone mass in women between 46 and 55 years of age. J Clin Periodontol. 1992; 19(7):492-6. DOI: 10.1111/j.1600-051x.1992.tb01162.x. View

Novak D, Bates B . Digital radiography: uses and limitations of the method. AJR Am J Roentgenol. 1989; 152(4):870-2. DOI: 10.2214/ajr.152.4.870. View

Reinbold W, Genant H, Reiser U, Harris S, Ettinger B . Bone mineral content in early-postmenopausal and postmenopausal osteoporotic women: comparison of measurement methods. Radiology. 1986; 160(2):469-78. DOI: 10.1148/radiology.160.2.3726129. View

Sandor T, Felsenberg D, Kalender W, CLAIN A, Brown E . Compact and trabecular components of the spine using quantitative computed tomography. Calcif Tissue Int. 1992; 50(6):502-6. DOI: 10.1007/BF00582162. View

Kalla A, Meyers O, Chalton D, Heath S, Brown G, Smith P . Increased metacarpal bone mass following 18 months of slow-acting antirheumatic drugs for rheumatoid arthritis. Br J Rheumatol. 1991; 30(2):91-100. DOI: 10.1093/rheumatology/30.2.91. View

Sartoris D, Resnick D . Dual-energy radiographic absorptiometry for bone densitometry: current status and perspective. AJR Am J Roentgenol. 1989; 152(2):241-6. DOI: 10.2214/ajr.152.2.241. View

Barnett E, Nordin B . The radiological diagnosis of osteoporosis: a new approach. Clin Radiol. 1960; 11:166-74. DOI: 10.1016/s0009-9260(60)80012-8. View

Strause L, Bracker M, Saltman P, Sartoris D, Kerr E . A comparison of quantitative dual-energy radiographic absorptiometry and dual photon absorptiometry of the lumbar spine in postmenopausal women. Calcif Tissue Int. 1989; 45(5):288-91. DOI: 10.1007/BF02556021. View

10.

Adams P, Davies G, Sweetnam P . Observer error and measurements of the metacarpal. Br J Radiol. 1969; 42(495):192-7. DOI: 10.1259/0007-1285-42-495-192. View

11.

MEEMA H . Improved vertebral fracture threshold in postmenopausal osteoporosis by radiogrametric measurements: its usefulness in selection for preventive therapy. J Bone Miner Res. 1991; 6(1):9-14. DOI: 10.1002/jbmr.5650060104. View

12.

MEEMA H, MEINDOK H . Advantages of peripheral radiogrametry over dual-photon absorptiometry of the spine in the assessment of prevalence of osteoporotic vertebral fractures in women. J Bone Miner Res. 1992; 7(8):897-903. DOI: 10.1002/jbmr.5650070806. View

13.

VIRTAMA P, MAHONEN H . Thickness of the cortical layer as an estimate of mineral content of human finger bones. Br J Radiol. 1960; 33:60-2. DOI: 10.1259/0007-1285-33-385-60. View

14.

Passloff E, Slap G, Pertschuk M, Attie M, Kaplan F . A longitudinal study of metacarpal bone morphometry in anorexia nervosa. Clin Orthop Relat Res. 1992; (278):217-25. View

15.

Rico Lenza H . [Bone mass measurement]. Med Clin (Barc). 1989; 93(8):292-4. View

16.

Dequeker J . Bone and ageing. Ann Rheum Dis. 1975; 34(1):100-15. PMC: 1006353. DOI: 10.1136/ard.34.1.100. View

17.

Rico H, Hernandez E, Revilla M, Villa L, Alvarez de Buergo M, Cuende E . Bone changes in postmenopausal Spanish women. Calcif Tissue Int. 1993; 52(2):103-6. DOI: 10.1007/BF00308317. View

18.

Szucs J, Horvath C, Kollin E, Szathmari M, HOLLO I . Three-year calcitonin combination therapy for postmenopausal osteoporosis with crush fractures of the spine. Calcif Tissue Int. 1992; 50(1):7-10. DOI: 10.1007/BF00297289. View

19.

Cosman F, Schnitzer M, McCann P, Parisien M, Dempster D, Lindsay R . Relationships between quantitative histological measurements and noninvasive assessments of bone mass. Bone. 1992; 13(3):237-42. DOI: 10.1016/8756-3282(92)90203-9. View

20.

. Clinical indications for bone mass measurements. A report from the Scientific Advisory Board of the National Osteoporosis Foundation. J Bone Miner Res. 1989; 4 Suppl 2:1-28. DOI: 10.1002/jbmr.5650040803. View