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Murine Complement Reduces Infectivity of Plasmodium Yoelii to Mosquitoes

Overview
Journal Infect Immun
Publisher American Society for Microbiology
Specialty Allergy & Immunology
Date 1995 Sep 1
PMID 7642309
Citations 9
Authors
T Tsuboi
Y M Cao
M Torii
Y Hitsumoto
H Kanbara
Affiliations
Soon will be listed here.
Abstract

The alternative pathway of complement in the mouse serum significantly reduced, but did not eliminate, the infectivity of Plasmodium yoelii to Anopheles stephensi. The reduction of the infectivity is mainly due to the inability of the zygote to transform into the ookinete in the mosquito midgut.

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References
1.
Nilsson U, MULLER-EBERHARD H . Deficiency of the fifth component of complement in mice with an inherited complement defect. J Exp Med. 1967; 125(1):1-16. PMC: 2138349. DOI: 10.1084/jem.125.1.1. View
2.
Collins F, Zavala F, Graves P, Cochrane A, Gwadz R, Akoh J . First field trial of an immunoradiometric assay for the detection of malaria sporozoites in mosquitoes. Am J Trop Med Hyg. 1984; 33(4):538-43. DOI: 10.4269/ajtmh.1984.33.538. View
3.
Grotendorst C, Carter R, Rosenberg R, Koontz L . Complement effects on the infectivity of Plasmodium gallinaceum to Aedes aegypti mosquitoes. I. Resistance of zygotes to the alternative pathway of complement. J Immunol. 1986; 136(11):4270-4. View
4.
Carter R, Kumar N, Quakyi I, Good M, Mendis K, Graves P . Immunity to sexual stages of malaria parasites. Prog Allergy. 1988; 41:193-214. View
5.
Kaslow D . Transmission-blocking immunity against malaria and other vector-borne diseases. Curr Opin Immunol. 1993; 5(4):557-65. DOI: 10.1016/0952-7915(93)90037-s. View