Enterocytes in the Follicle-associated Epithelia of Rabbit Small Intestine Display Distinctive Lectin-binding Properties

Overview

Journal Histochem Cell Biol

Publisher Springer

Specialties Biochemistry
Cell Biology

Date 1995 Feb 1

PMID 7634152

Citations 4

Authors

M A Jepson

C M Mason

N L Simmons

B H Hirst

Affiliations

Soon will be listed here.

Abstract

Glycoconjugate expression in follicle-associated epithelia has been examined by application of a panel of lectins to fixed preparations of rabbit small intestine, including Peyer's patches. Each of the lectins examined (wheat germ agglutinin, peanut agglutinin, Ulex europaeus agglutinin I and Bandeiraea simplicifolia agglutinin II) exhibited a lower affinity for the apical surface of the specialised M cells than to columnar enterocytes within the Peyer's patch follicle-associated epithelium. Peanut agglutinin differed from the other lectins examined in that it displayed a markedly higher affinity for enterocytes within the follicle-associated epithelium than the neighbouring villi. This observation reveals that the specialised development of the follicle-associated epithelium involves expression of distinctive surface properties within the enterocyte population in addition to the more widely documented heterogeneous development of enterocytes and the specialised M cells.

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