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Hepatitis C and Hepatocellular Carcinoma

Overview
Journal Semin Liver Dis
Publisher Thieme
Specialty Gastroenterology
Date 1995 Feb 1
PMID 7597445
Citations 33
Authors
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Abstract

Sufficient evidence has accumulated that chronic infection with HCV substantially increases the risk of HCC, particularly in the presence of cirrhosis. HCV appears to represent a major underlying cause of HCC in southern Europe and Japan, regions where HCC incidence is intermediate, whereas its impact is smaller in sub-Saharan Africa and China, where HBV-related HCC predominates, and in the developed western world, where the majority of cases of HCC are associated with cirrhosis of unknown etiology.

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