Characterization of Toxin-producing Cyanobacteria by Using an Oligonucleotide Probe Containing a Tandemly Repeated Heptamer

Overview

Journal J Bacteriol

Publisher American Society for Microbiology

Specialty Microbiology

Date 1995 Oct 1

PMID 7592362

Citations 19

Authors

L Rouhiainen

K Sivonen

W J Buikema

R Haselkorn

Affiliations

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Abstract

Cyanobacteria produce toxins that kill animals. The two main classes of cyanobacterial toxins are cyclic peptides that cause liver damage and alkaloids that block nerve transmission. Many toxin-producing strains from Finnish lakes were brought into axenic culture, and their toxins were characterized. Restriction fragment length polymorphism analysis, probing with a short tandemly repeated DNA sequence found at many locations in the chromosome of Anabaena sp. strain PCC 7120, distinguishes hepatotoxic Anabaena isolates from neurotoxin-producing strains and from Nostoc spp.

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