Organization and Transcription of the Mitochondrial ATP Synthase Genes in the Yeast Yarrowia Lipolytica

Overview

Journal Curr Genet

Specialty Genetics

Date 1994 Nov 1

PMID 7533057

Citations 3

Authors

M Matsuoka

M Matsubara

J Inoue

M Kakehi

T Imanaka

Affiliations

Soon will be listed here.

Abstract

Mitochondrial gene organization was studied in a dimorphic yeast, Yarrowia lipoltica. The gene order in a sequenced 6.6-kilobase region closely resembles that of the human mitochondrial genome in that ATP synthase subunit 8 and 6 genes are followed by genes for cytochrome c oxidase subunit 3 (which contains an intron), NADH-ubiquinone oxidoreductase subunit 4, and ATP synthase subunit 9. This region also contains tRNA genes decoding AUA, UGA, CUN and CCN codons, suggesting a unique mitochondrial translation. All the above genes are transcribed from the same DNA strand into multigenic RNAs, starting from a nonanucleotide sequence, 5'-ATATAAATA-3', similar to other yeast mitochondrial promoters.

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Kolondra A, Labedzka-Dmoch K, Wenda J, Drzewicka K, Golik P BMC Genomics. 2015; 16:827.

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The complete mitochondrial genome of yarrowia lipolytica.

Kerscher S, Durstewitz G, Casaregola S, Gaillardin C, Brandt U Comp Funct Genomics. 2008; 2(2):80-90.

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Homologous maturase-like proteins are encoded within the group I introns in different mitochondrial genes specifying Yarrowia lipolytica cytochrome c oxidase subunit 3 and Saccharomyces cerevisiae apocytochrome b.

Matsuoka M, Matsubara M, Kakehi M, Imanaka T Curr Genet. 1994; 26(5-6):377-81.

PMID: 7533056 DOI: 10.1007/BF00309922.

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