Chicken Lens Crystallin DNA Sequences Show at Least Two Delta-crystallin Genes

Overview

Journal Nature

Specialty Science

Date 1980 Mar 20

PMID 7360254

Citations 15

Authors

S P Bhat

R E Jones

M A Sullivan

J Piatigorsky

Affiliations

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Abstract

Restriction analysis of chicken DNA using probes derived from a cloned cDNA and analysis of cloned genomic DNA fragments containing delta-crystallin gene sequences have indicated the presence of at least two non-allelic genes for delta-crystallin, the first and principal crystallin synthesised in the embryonic chicken lens. Electron microscopic analyses of three cloned genomic fragments revealed that the delta-crystallin mRNA gene sequences are interrupted at least 14 times in one of the delta-crystallin genes.

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