Alpha 2.0
Login Register
» Articles » PMID: 7251824

Immunoglobulin E Anti-Staphylococcus Aureus Antibodies in Atopic Patients

Overview
Journal J Clin Microbiol
Specialty Microbiology
Date 1981 Jun 1
PMID 7251824
Citations 11
Authors
G A Walsh
K L Richards
S D Douglas
M N Blumenthal
Affiliations
Soon will be listed here.
Abstract

Sera from 56 patient and normal adults were examined to quantitate total immunoglobulin E (IgE) and IgE antibodies to Staphylococcus aureus and Staphylococcus epidermidis. Patients were divided into six groups based on clinical symptoms; a seventh group consisted of normal adults. Anti-S, aureus IgE binding was significantly higher in three groups of patients (those with eczema, those with or without series staphylococcal abscesses, and allergic patients with staphylococcal skin infections) than it was in the control group. Patients with high IgE due to allergies or parasitic infections without staphylococcal infections and patients with low or normal IgE and serious staphylococcal infection showed low levels of binding. The assay measured specific binding of IgE to bacterial antigens.

Citing Articles

IgE-activated mast cells enhance TLR4-mediated antigen-specific CD4 T cell responses.

Phong B, DSouza S, Baudier R, Wu E, Immethun V, Bauer D Sci Rep. 2021; 11(1):9686.

PMID: 33958642 PMC: 8102524. DOI: 10.1038/s41598-021-88956-4.

House dust mites as potential carriers for IgE sensitization to bacterial antigens.

Dzoro S, Mittermann I, Resch-Marat Y, Vrtala S, Nehr M, Hirschl A Allergy. 2017; 73(1):115-124.

PMID: 28741705 PMC: 5763376. DOI: 10.1111/all.13260.

The hyperimmunoglobulin E syndrome--clinical manifestation diversity in primary immune deficiency.

Szczawinska-Poplonyk A, Kycler Z, Pietrucha B, Heropolitanska-Pliszka E, Breborowicz A, Gerreth K Orphanet J Rare Dis. 2011; 6:76.

PMID: 22085750 PMC: 3226432. DOI: 10.1186/1750-1172-6-76.

Immunoglobulin E antibody reactivity to bacterial antigens in atopic dermatitis patients.

Reginald K, Westritschnig K, Werfel T, Heratizadeh A, Novak N, Focke-Tejkl M Clin Exp Allergy. 2010; 41(3):357-69.

PMID: 21155910 PMC: 3057935. DOI: 10.1111/j.1365-2222.2010.03655.x.

The hyper-IgE syndrome.

Buckley R Clin Rev Allergy Immunol. 2001; 20(1):139-54.

PMID: 11269224 DOI: 10.1385/CRIAI:20:1:139.

References
1.
Davis S, Schaller J, Wedgwood R . Job's Syndrome. Recurrent, "cold", staphylococcal abscesses. Lancet. 1966; 1(7445):1013-5. DOI: 10.1016/s0140-6736(66)90119-x. View
2.
Buckley R, Wray B, Belmaker E . Extreme hyperimmunoglobulinemia E and undue susceptibility to infection. Pediatrics. 1972; 49(1):59-70. View
3.
Ceska M, Lundkvist U . A new and simple radioimmunoassay method for the determination of IgE. Immunochemistry. 1972; 9(10):1021-30. DOI: 10.1016/0019-2791(72)90112-7. View
4.
Hill H, Quie P . Raised serum-IgE levels and defective neutrophil chemotaxis in three children with eczema and recurrent bacterial infections. Lancet. 1974; 1(7850):183-7. DOI: 10.1016/s0140-6736(74)92493-3. View
5.
Rogge J, Hanifin J . Immunodeficiencies in severe atopic dermatitis. Depressed chemotaxis and lymphocyte transformation. Arch Dermatol. 1976; 112(10):1391-6. View