Quantitative Assessment of Smooth-pursuit Eye Movements in Healthy and Epileptic Subjects

Overview

Journal J Neurol Neurosurg Psychiatry

Publisher BMJ Publishing Group

Specialties Neurology
Neurosurgery
Psychiatry

Date 1980 Dec 1

PMID 7217958

Citations 7

Authors

P R Bittencourt

M A Gresty

A Richens

Affiliations

Soon will be listed here.

Abstract

A quantitative electro-oculographic method was used to assess the impairment in smooth-pursuit and vestibulo-ocular reflex suppression eye movements in 12 epileptic patients and eight normal volunteers. Both types of eye movement were impaired by a factor of 40% in the epileptic patients, and the impairment was at least partly due to the treatment with phenytoin and phenobarbitone. There was a strong positive correlation between the performances in vestibulo-ocular reflex suppression and smooth-pursuit.

Citing Articles

Pharmacological treatment effects on eye movement control.

Reilly J, Lencer R, Bishop J, Keedy S, Sweeney J Brain Cogn. 2008; 68(3):415-35.

PMID: 19028266 PMC: 3159189. DOI: 10.1016/j.bandc.2008.08.026.

The relationship between peak velocity of saccadic eye movements and serum benzodiazepine concentration.

Bittencourt P, Wade P, Smith A, Richens A Br J Clin Pharmacol. 1981; 12(4):523-33.

PMID: 6794587 PMC: 1401908. DOI: 10.1111/j.1365-2125.1981.tb01261.x.

Effect of amphetamine on saccadic and smooth pursuit eye movements.

Tedeschi G, Bittencourt P, Smith A, Richens A Psychopharmacology (Berl). 1983; 79(2-3):190-2.

PMID: 6405428 DOI: 10.1007/BF00427810.

Specific oculomotor deficits after amylobarbitone.

Tedeschi G, Bittencourt P, Smith A, Richens A Psychopharmacology (Berl). 1983; 79(2-3):187-9.

PMID: 6405427 DOI: 10.1007/BF00427809.

Benzodiazepines impair smooth pursuit eye movements.

Bittencourt P, Wade P, Smith A, Richens A Br J Clin Pharmacol. 1983; 15(2):259-62.

PMID: 6133544 PMC: 1427870. DOI: 10.1111/j.1365-2125.1983.tb01495.x.

References

Franck M, KUHLO W . [Effects of alcohol on directed saccadic eye movements in man]. Arch Psychiatr Nervenkr (1970). 1970; 213(3):238-45. DOI: 10.1007/BF00342660. View

Norris H . The action of sedatives on brain stem oculomotor systems in man. Neuropharmacology. 1971; 10(21):181-91. DOI: 10.1016/0028-3908(71)90039-6. View

Holzman P, PROCTOR L, Hughes D . Eye-tracking patterns in schizophrenia. Science. 1973; 181(4095):179-81. DOI: 10.1126/science.181.4095.179. View

Plaa G . Acute toxicity of antiepileptic drugs. Epilepsia. 1975; 16(1):183-91. DOI: 10.1111/j.1528-1157.1975.tb04734.x. View

Baloh R, Konrad H, Sills A, Honrubia V . The saccade velocity test. Neurology. 1975; 25(11):1071-6. DOI: 10.1212/wnl.25.11.1071. View

SHAGASS C, Roemer R, AMADEO M . Eye-tracking performance and engagement of attention. Arch Gen Psychiatry. 1976; 33(1):121-5. DOI: 10.1001/archpsyc.1976.01770010077015. View

Baloh R, Kumley W, Sills A, Honrubia V, Konrad H . Quantitative measurement of smooth pursuit eye movements. Ann Otol Rhinol Laryngol. 1976; 85(1 Pt 1):111-9. DOI: 10.1177/000348947608500120. View

Gresty M, Trinder E, Leech J . Perception of everyday visual environments during saccadic eye movements. Aviat Space Environ Med. 1976; 47(9):991-2. View

Trimble M, Reynolds E . Anticonvulsant drugs and mental symptoms: a review. Psychol Med. 1976; 6(2):169-78. DOI: 10.1017/s0033291700013726. View

10.

Baloh R, Honrubia V, Sills A . Eye-tracking and optokinetic nystagmus. Results of quantitative testing in patients with well-defined nervous system lesions. Ann Otol Rhinol Laryngol. 1977; 86(1 Pt 1):108-14. DOI: 10.1177/000348947708600119. View

11.

Umeda Y, Sakata E . Equilibrium disorder in carbamazepine toxicity. Ann Otol Rhinol Laryngol. 1977; 86(3 Pt 1):318-22. DOI: 10.1177/000348947708600307. View

12.

Gresty M, Leech J . Coordination of the head and eyes in pursuit of predictable and random target motion. Aviat Space Environ Med. 1977; 48(8):741-4. View

13.

Benson A, Barnes G . Vision during angular oscillation: the dynamic interaction of visual and vestibular mechanisms. Aviat Space Environ Med. 1978; 49(1 Pt. 2):340-5. View

14.

Babin R . ENG of the month: Dilantin suppression. Ann Otol Rhinol Laryngol. 1978; 87(2 Pt 1):284-5. DOI: 10.1177/000348947808700226. View

15.

Salcman M, Defendini R, Correll J, Gilman S . Neuropathological changes in cerebellar biopsies of epileptic patients. Ann Neurol. 1978; 3(1):10-9. DOI: 10.1002/ana.410030104. View

16.

Dichgans J, von Reutern G, Rommelt U . Impaired suppression of vestibular nystagmus by fixation in cerebellar and noncerebellar patients. Arch Psychiatr Nervenkr (1970). 1978; 226(3):183-99. DOI: 10.1007/BF00341710. View

17.

Hood J, Korres S . Vestibular suppression in peripheral and central vestibular disorders. Brain. 1979; 102(4):785-804. DOI: 10.1093/brain/102.4.785. View

18.

Halmagyi G, Gresty M . Clinical signs of visual-vestibular interaction. J Neurol Neurosurg Psychiatry. 1979; 42(10):934-9. PMC: 490367. DOI: 10.1136/jnnp.42.10.934. View

19.

RASHBASS C . The relationship between saccadic and smooth tracking eye movements. J Physiol. 1961; 159:326-38. PMC: 1359508. DOI: 10.1113/jphysiol.1961.sp006811. View