Specification of Cell Morphology by Endogenous Determinants

Overview

Journal J Cell Biol

Specialty Cell Biology

Date 1981 Sep 1

PMID 7197278

Citations 18

Authors

F Solomon

Affiliations

Soon will be listed here.

Abstract

We are studying the mechanisms by which cells elaborate their differentiated morphologies. Here we discuss one aspect of this issue: the specification of the detailed shape of individual cells. We describe an experimental system in which endogenous determinants of morphology are expressed. These determinants originally were detected in the morphological relationships between sister neuroblastoma cells. Approaches to analyzing these relationships are presented. The properties and behavior of the endogenous determinants have been partially characterized by further experiments, which are also described. The significance and the prospects for further analysis of our findings are discussed.

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