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Tumor Cell Line Characterization of a Malignant Histiocytosis Transplanted into Nude Mice

Overview

Overview

Journal Virchows Arch A Pathol Anat Histol

Specialty Pathology

Date 1982 Jan 1

PMID 7179735

Citations 1

Authors

Authors

M F Rousseau-Merck

F Jaubert

M A Bach

P Niaudet

D Cottreau

C NEZELOF

Affiliations

Affiliations

Soon will be listed here.

Abstract

The successful transplantation of a human malignant histiocytosis into nude mice allowed the examination of its atypical histiocytic cell proliferation. Histiocytic type cells were identified by positive reactions with acid phosphatase and non-specific esterase and with anti human DR or OKI1 antisera. Presence of OKT9 antigen and negative results obtained with most OKT antisera, rosettes, erythrophagocytosis and lysozyme corroborate the histiocytic immature state of the cells and preclude another type of tumor. All positive tests to prove a mature mononuclear phagocytic origin were attributable to the murine host cell reaction.

Citing Articles

Transplantability in nude mice of embryonic and other childhood tumours.

Rousseau-Merck M, BIGEL P, Mouly H, Flamant F, Zucker J, Wache A Br J Cancer. 1985; 52(2):279-83.

PMID: 2992567 PMC: 1977113. DOI: 10.1038/bjc.1985.189.

References

1.

Kahn A, Boivin P, Rubinson H, Cottreau D, Marie J, DREYFUS J . Modifications of purified glucose-6-phosphate dehydrogenase and other enzymes by a factor of low molecular weight abundant in some leukemic cells. Proc Natl Acad Sci U S A. 1976; 73(1):77-81. PMC: 335842. DOI: 10.1073/pnas.73.1.77. View

2.

Nelson M, Nelson D, Hopper K . I. Tumor growth in mice with depressed capacity to mount inflammatory responses: possible role of macrophages. Am J Pathol. 1981; 104(2):114-24. PMC: 1903754. View

3.

Bertrand O, Kahn A, Cottreau D, Boivin P . Human leukocyte glucose-phosphate-isomerase purification by affinity elution and immunological study. Biochimie. 1976; 58(3):261-7. DOI: 10.1016/s0300-9084(76)80432-4. View

4.

Lampert I, Catovsky D, Bergier N . Malignant histiocytosis: a clinico-pathological study of 12 cases. Br J Haematol. 1978; 40(1):65-77. DOI: 10.1111/j.1365-2141.1978.tb03640.x. View

5.

Aisenberg A, Wilkes B . Unusual human lymphoma phenotype defined by monoclonal antibody. J Exp Med. 1980; 152(4):1126-31. PMC: 2185966. DOI: 10.1084/jem.152.4.1126. View

6.

Reinherz E, Kung P, Goldstein G, Levey R, Schlossman S . Discrete stages of human intrathymic differentiation: analysis of normal thymocytes and leukemic lymphoblasts of T-cell lineage. Proc Natl Acad Sci U S A. 1980; 77(3):1588-92. PMC: 348542. DOI: 10.1073/pnas.77.3.1588. View

7.

Huhn D, Meister P, Wilmanns W . Malignant histiocytosis. Clinical findings and therapy. Klin Wochenschr. 1980; 58(1):31-5. DOI: 10.1007/BF01477141. View

8.

Bianco C, Patrick R, NUSSENZWEIG V . A population of lymphocytes bearing a membrane receptor for antigen-antibody-complement complexes. I. Separation and characterization. J Exp Med. 1970; 132(4):702-20. PMC: 2138865. DOI: 10.1084/jem.132.4.702. View

9.

Haynes B, Hemler M, Cotner T, Mann D, Eisenbarth G, Strominger J . Characterization of a monoclonal antibody (5E9) that defines a human cell surface antigen of cell activation. J Immunol. 1981; 127(1):347-51. View

10.

Meister P, Nathrath W . Immunohistochemical markers of histiocytic tumors. Hum Pathol. 1980; 11(3):300-1. DOI: 10.1016/s0046-8177(80)80016-5. View

11.

Johnsen H, Madsen M . Lymphocyte subpopulations in man: ox erythrocytes as indicators in the EA- and EAC-rosette tests: serological and technical aspects. Scand J Immunol. 1978; 8(3):247-56. DOI: 10.1111/j.1365-3083.1978.tb00517.x. View

12.

Kung P, Goldstein G, Reinherz E, Schlossman S . Monoclonal antibodies defining distinctive human T cell surface antigens. Science. 1979; 206(4416):347-9. DOI: 10.1126/science.314668. View

13.

Rausch P, HERION J, Carney C, Weinstein P . Malignant histiocytosis: a cytochemical and electron microscopic study of an unusual case. Cancer. 1979; 44(6):2158-64. DOI: 10.1002/1097-0142(197912)44:6<2158::aid-cncr2820440628>3.0.co;2-1. View

14.

Mendelsohn G, Eggleston J, Mann R . Relationship of lysozyme (muramidase) to histiocytic differentiation in malignant histocytosis: an immunohistochemical study. Cancer. 1980; 45(2):273-9. DOI: 10.1002/1097-0142(19800115)45:2<273::aid-cncr2820450212>3.0.co;2-j. View

15.

Welsh K, Turner M . Preparation of antisera specific for human B cells by immunization of rabbits with immune complexes. Tissue Antigens. 1976; 8(3):197-205. DOI: 10.1111/j.1399-0039.1976.tb00569.x. View

16.

Halper J, Knowles 2nd D, Wang C . Ia antigen expression by human malignant lymphomas: correlation with conventional lymphoid markers. Blood. 1980; 55(3):373-82. View

17.

RILKE F, Carbone A, Musumeci R, Pilotti S, De Lena M, Bonadonna G . Malignant histiocytosis: a clinicopathologic study of 18 consecutive cases. Tumori. 1978; 64(2):211-27. DOI: 10.1177/030089167806400211. View

18.

Tubbs R, Sheibani K, Sebek B, Savage R . Malignant histiocytosis. Ultrastructural and immunocytochemical characterization. Arch Pathol Lab Med. 1980; 104(1):26-9. View

19.

Lombardi L, Carbone A, Pilotti S, RILKE F . Malignant histiocytosis: a histological and ultrastructural study of lymph nodes in six cases. Histopathology. 1978; 2(5):315-28. DOI: 10.1111/j.1365-2559.1978.tb01724.x. View

20.

Warnke R, Kim H, DORFMAN R . Malignant histiocytosis (histiocytic medullary reticulosis). I. Clinicopatholigic study of 29 cases. Cancer. 1975; 35(1):215-30. DOI: 10.1002/1097-0142(197501)35:1<215::aid-cncr2820350127>3.0.co;2-h. View