Polyvalent Heat-killed Antigen for the Diagnosis of Infection with Legionella Pneumophila

Overview

Journal J Clin Pathol

Specialty Pathology

Date 1982 Apr 1

PMID 7042762

Citations 6

Authors

R J Fallon

W H Abraham

Affiliations

Soon will be listed here.

Abstract

A polyvalent antigen composed of heat-killed agar-grown Legionella pneumophila serogroups 1-4 suspended in a suspension of yolk-sac from embryonated hens' eggs has been examined for use in the indirect fluorescent antibody test for Legionella infection. The serological response detected by monovalent antigen correlated well with that detected by polyvalent antigen. The use of polyvalent antigen forms a useful screening test for the detection of antibody to L pneumophila, but positive results must be confirmed by test using monovalent antigen.

Citing Articles

Legionella and Legionnaires' disease: 25 years of investigation.

Fields B, Benson R, Besser R Clin Microbiol Rev. 2002; 15(3):506-26.

PMID: 12097254 PMC: 118082. DOI: 10.1128/CMR.15.3.506-526.2002.

Legionella infections in Scotland.

Fallon R J Hyg (Lond). 1982; 89(3):439-48.

PMID: 7153509 PMC: 2134247. DOI: 10.1017/s002217240007100x.

Formalised yolk sac antigen in early diagnosis of Legionnaires' disease caused by Legionella pneumophila serogroup 1.

Fallon R, Abraham W J Clin Pathol. 1982; 35(7):791-2.

PMID: 7096602 PMC: 497780. DOI: 10.1136/jcp.35.7.791.

Oropharyngeal colonization with Legionella pneumophila.

Bridge J, Edelstein P J Clin Microbiol. 1983; 18(5):1108-12.

PMID: 6358250 PMC: 272850. DOI: 10.1128/jcm.18.5.1108-1112.1983.

Proximity of the home to a cooling tower and risk of non-outbreak Legionnaires' disease.

Bhopal R, Fallon R, Buist E, Black R, Urquhart J BMJ. 1991; 302(6773):378-83.

PMID: 2004142 PMC: 1676166. DOI: 10.1136/bmj.302.6773.378.

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