PJT2: Unusual H1 Plasmid in a Highly Virulent Lactose-positive and Chloramphenicol-resistant Salmonella Typhimurium Strain from Calves

Overview

Journal Antimicrob Agents Chemother

Publisher American Society for Microbiology

Specialty Pharmacology

Date 1980 Sep 1

PMID 6999986

Citations 4

Authors

J F Timoney

D E Taylor

S Shin

P McDonough

Affiliations

Soon will be listed here.

Abstract

A lactose-positive and chloramphenicol-resistant strain of Salmonella typhimurium of high virulence was isolated from an outbreak of enteric and septicemic salmonellosis in veal calves. the lactose-positive marker was located on an H1 plasmid, pJT2, together with resistance to chloramphenicol, streptomycin, sulfonamides, and tetracycline, pJT2 was unusually large and had a molecular weight of about 150 X 10(6). A similar plasmid was also present in a third of the Escherichia coli strains isolated from the intestines of septicemic calves during the outbreak. Spontaneously derived Lac- derivatives of pJT2 had an approximate molecular weight of 140 X 10(6).

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