Curing of Escherichia Coli K12 Plasmids by Coumermycin

Overview

Journal Mol Gen Genet

Specialties Genetics
Molecular Biology

Date 1980 Apr 1

PMID 6991878

Citations 19

Authors

O N Danilevskaya

A I Gragerov

Affiliations

Soon will be listed here.

Abstract

Low concentrations of the antibiotic coumermycin A1, the inhibitor of bacterial DNA gyrase, effectively eliminate pBR322, pMB9 and other ColE 1 related plasmids from E. coli K12 strains. The curing action of antibiotic seems to result from the plasmid degradation and not just from the inhibition of replication.

Citing Articles

Strategies to combat antimicrobial resistance: anti-plasmid and plasmid curing.

Buckner M, Ciusa M, Piddock L FEMS Microbiol Rev. 2018; 42(6):781-804.

PMID: 30085063 PMC: 6199537. DOI: 10.1093/femsre/fuy031.

TonB-dependent transporter FhuA in planar lipid bilayers: partial exit of its plug from the barrel.

Udho E, Jakes K, Finkelstein A Biochemistry. 2012; 51(34):6753-9.

PMID: 22846061 PMC: 3448877. DOI: 10.1021/bi300493u.

Mutations which alter the elbow region of tRNA2Gly reduce T4 gene 60 translational bypassing efficiency.

Herr A, Atkins J, GESTELAND R EMBO J. 1999; 18(10):2886-96.

PMID: 10329634 PMC: 1171369. DOI: 10.1093/emboj/18.10.2886.

phnE and glpT genes enhance utilization of organophosphates in Escherichia coli K-12.

Elashvili I, Defrank J, Culotta V Appl Environ Microbiol. 1998; 64(7):2601-8.

PMID: 9647836 PMC: 106432. DOI: 10.1128/AEM.64.7.2601-2608.1998.

Biological activity of new aza analogues of quinolones.

Belicova A, Seman M, Milata V, Ilavsky D, Ebringer L Folia Microbiol (Praha). 1997; 42(3):193-8.

PMID: 9246761 DOI: 10.1007/BF02818977.

References

Clewell D, Evenchik B, Cranston J . Direct inhibition of Col E 1 plasmid DNA replication in Escherichia coli by rifampicin. Nat New Biol. 1972; 237(70):29-31. DOI: 10.1038/newbio237029a0. View

Bass I, Danilevskaya O, Mekhedov S, Fedoseeva V, Gorlenko Z . The effect of rifampicin upon the transcription of RNA polymerase beta-gene in Escherichia coli. Mol Gen Genet. 1979; 173(1):101-7. DOI: 10.1007/BF00267695. View

Durkacz B, Sherratt D . Segregation kinetics of colicinogenic factor col E1 from a bacterial population temperature sensitive for DNA polymerase I. Mol Gen Genet. 1973; 121(1):71-5. DOI: 10.1007/BF00353694. View

Blair D, Sherratt D, Clewell D, Helinski D . Isolation of supercoiled colicinogenic factor E 1 DNA sensitive to ribonuclease and alkali. Proc Natl Acad Sci U S A. 1972; 69(9):2518-22. PMC: 426978. DOI: 10.1073/pnas.69.9.2518. View

Hayward G . Gel electrophoretic separation of the complementary strands of bacteriophage DNA. Virology. 1972; 49(1):342-4. DOI: 10.1016/s0042-6822(72)80042-4. View

Bedbrook J, Ausubel F . Recombination between bacterial plasmids leading to the formation of plasmid multimers. Cell. 1976; 9(4 PT 2):707-16. DOI: 10.1016/0092-8674(76)90134-3. View

Mizuuchi K, ODea M, Gellert M . DNA gyrase: subunit structure and ATPase activity of the purified enzyme. Proc Natl Acad Sci U S A. 1978; 75(12):5960-3. PMC: 393096. DOI: 10.1073/pnas.75.12.5960. View

Sugino A, Peebles C, Kreuzer K, Cozzarelli N . Mechanism of action of nalidixic acid: purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme. Proc Natl Acad Sci U S A. 1977; 74(11):4767-71. PMC: 432036. DOI: 10.1073/pnas.74.11.4767. View

Gellert M, ODea M, Itoh T, Tomizawa J . Novobiocin and coumermycin inhibit DNA supercoiling catalyzed by DNA gyrase. Proc Natl Acad Sci U S A. 1976; 73(12):4474-8. PMC: 431506. DOI: 10.1073/pnas.73.12.4474. View

10.

Bolivar F, Rodriguez R, Greene P, Betlach M, Heyneker H, Boyer H . Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. Gene. 1977; 2(2):95-113. View

11.

Mirkin S, Bogdanova E, Gorlenko Z, Gragerov A, Larionov O . DNA supercoiling and transcription in Escherichia coli: influence of RNA polymerase mutations. Mol Gen Genet. 1979; 177(1):169-75. DOI: 10.1007/BF00267267. View

12.

Sugino A, Higgins N, Brown P, Peebles C, Cozzarelli N . Energy coupling in DNA gyrase and the mechanism of action of novobiocin. Proc Natl Acad Sci U S A. 1978; 75(10):4838-42. PMC: 336216. DOI: 10.1073/pnas.75.10.4838. View

13.

Cohen S, Chang A . Recircularization and autonomous replication of a sheared R-factor DNA segment in Escherichia coli transformants. Proc Natl Acad Sci U S A. 1973; 70(5):1293-7. PMC: 433482. DOI: 10.1073/pnas.70.5.1293. View

14.

Inselburg J . ColE1 plasmid mutants affecting growth of an Escherichia coli recB recC sbcB mutant. J Bacteriol. 1978; 133(1):433-6. PMC: 222034. DOI: 10.1128/jb.133.1.433-436.1978. View

15.

CLOWES R . Molecular structure of bacterial plasmids. Bacteriol Rev. 1972; 36(3):361-405. PMC: 378457. DOI: 10.1128/br.36.3.361-405.1972. View