Enterotoxigenic Escherichia Coli in Central Canada

Overview

Journal J Clin Microbiol

Specialty Microbiology

Date 1980 Apr 1

PMID 6989856

Citations 16

Authors

J Brunton

D Hinde

C Langston

R Gross

B Rowe

M Gurwith

Affiliations

Soon will be listed here.

Abstract

During epidemiological studies carried out in urban and rural areas of the midwestern Canadian province of Manitoba, we cultured enterotoxigenic Escherichia coli (ETEC) from 16 (1.7%) of 945 diarrheal stools and 4 (0.3%) of 1,282 normal stools. ETEC was found in not more than 2.3% of diarrheal stools obtained from any population during any season. Diarrhea associated with ETEC persisted for a mean of 9 days. Two children were dehydrated and required intravenous fluid therapy, and one adult suffered a cholera-like syndrome. Half of the children required hospitalization for management of their diarrhea. Two adults and two children who harbored ETEC were completely asymptomatic. The pattern of toxin production correlated with serotype and the serotypes encountered were (with a few exceptions) similar to those found in other areas. We conclude that ETEC is an uncommon cause of diarrhea, both in rural and urban areas of central Canada. However, the possibility that ETEC might cause severe sporadic cases or epidemics of gastroenteritis remains.

Citing Articles

In vitro activities of cephalosporins and quinolones against Escherichia coli strains isolated from diarrheic dairy calves.

Orden J, Ruiz-Santa-Quiteria J, Garcia S, Cid D, De La Fuente R Antimicrob Agents Chemother. 1999; 43(3):510-3.

PMID: 10049259 PMC: 89152. DOI: 10.1128/AAC.43.3.510.

In vitro susceptibility of Escherichia coli strains isolated from diarrhoeic lambs and goat kids to 14 antimicrobial agents.

Cid D, Piriz S, Ruiz-Santa-Quiteria J, Valle J, Vadillo S, De La Fuente R J Vet Pharmacol Ther. 1996; 19(5):397-401.

PMID: 8905575 PMC: 7194150. DOI: 10.1111/j.1365-2885.1996.tb00070.x.

Serotypes and colonization factors of enterotoxigenic Escherichia coli isolated in various countries.

Blanco J, Blanco M, Gonzalez E, Blanco J, Alonso M, Garabal J Eur J Epidemiol. 1993; 9(5):489-96.

PMID: 8307133 DOI: 10.1007/BF00209526.

Serotypes of enterotoxigenic Escherichia coli isolated in the United States.

DeBoy 2nd J, Wachsmuth I, Davis B Infect Immun. 1980; 29(2):361-8.

PMID: 7011973 PMC: 551126. DOI: 10.1128/iai.29.2.361-368.1980.

Enterotoxigenic and enteropathogenic Escherichia coli in Galicia (north-west Spain).

Blanco J, Gonzalez E, Bernardez I, Varela B Med Microbiol Immunol. 1983; 172(3):165-9.

PMID: 6358820 DOI: 10.1007/BF02123802.

References

BAUER A, KIRBY W, SHERRIS J, Turck M . Antibiotic susceptibility testing by a standardized single disk method. Am J Clin Pathol. 1966; 45(4):493-6. View

Dean A, Ching Y, Williams R, Harden L . Test for Escherichia coli enterotoxin using infant mice: application in a study of diarrhea in children in Honolulu. J Infect Dis. 1972; 125(4):407-11. DOI: 10.1093/infdis/125.4.407. View

Tulloch Jr E, Ryan K, Formal S, FRANKLIN F . Invasive enteropathic Escherichia coli dysentery. An outbreak in 28 adults. Ann Intern Med. 1973; 79(1):13-7. DOI: 10.7326/0003-4819-79-1-13. View

Shore E, Dean A, Holik K, Davis B . Enterotoxin-producing Escherichia coli and diarrheal disease in adult travelers: a prospective study. J Infect Dis. 1974; 129(5):577-82. DOI: 10.1093/infdis/129.5.577. View

Flewett T, Davies H, Bryden A, Robertson M . Diagnostic electron microscopy of faeces. II. Acute gastroenteritis associated with reovirus-like particles. J Clin Pathol. 1974; 27(8):608-14. PMC: 475412. DOI: 10.1136/jcp.27.8.608. View

Sack D, Sack R . Test for enterotoxigenic Escherichia coli using Y-1 adrenal cells in miniculture. Infect Immun. 1975; 11(2):334-6. PMC: 415066. DOI: 10.1128/iai.11.2.334-336.1975. View

Gorbach S, KEAN B, Evans D, Evans Jr D, BESSUDO D . Travelers' diarrhea and toxigenic Escherichia coli. N Engl J Med. 1975; 292(18):933-6. DOI: 10.1056/NEJM197505012921801. View

Sack R, Hirschhorn N, BROWNLEE I, Cash R, Woodward W, Sack D . Enterotoxigenic Escherichia-coli-associated diarrheal disease in Apache children. N Engl J Med. 1975; 292(20):1041-5. DOI: 10.1056/NEJM197505152922001. View

Sack D, Merson M, Wells J, Sack R, Morris G . Diarrhoea associated with heat-stable enterotoxin-producing strains of Escherichia coli. Lancet. 1975; 2(7928):239-41. DOI: 10.1016/s0140-6736(75)90958-7. View

10.

Guerrant R, Moore R, Kirschenfeld P, Sande M . Role of toxigenic and invasive bacteria in acute diarrhea of childhood. N Engl J Med. 1975; 293(12):567-72. DOI: 10.1056/NEJM197509182931201. View

11.

Echeverria P, Blacklow N, Smith D . Role of heat-labile toxigenic Escherichia coli and Reovirus-like agent in diarrhoea in Boston children. Lancet. 1975; 2(7945):1113-6. DOI: 10.1016/s0140-6736(75)91004-1. View

12.

Nalin D, McLAUGHLIN J, Rahaman M, Yunus M, Curlin G . Enterotoxigenic Escherichia coli and idiopathic diarrhoea in Bangladesh. Lancet. 1975; 2(7945):1116-9. DOI: 10.1016/s0140-6736(75)91005-3. View

13.

ORSKOV F, ORSKOV I . Escherichia coli O:H serotypes isolated from human blood. Prevalence of the K1 antigen with technical details of O and H antigenic determination. Acta Pathol Microbiol Scand Suppl. 1975; 83(6):595-600. View

14.

Kapikian A, Kim H, Wyatt R, Cline W, Arrobio J, BRANDT C . Human reovirus-like agent as the major pathogen associated with "winter" gastroenteritis in hospitalized infants and young children. N Engl J Med. 1976; 294(18):965-72. DOI: 10.1056/NEJM197604292941801. View

15.

Merson M, Morris G, Sack D, Wells J, Feeley J, Sack R . Travelers' diarrhea in Mexico. A prospective study of physicians and family members attending a congress. N Engl J Med. 1976; 294(24):1299-305. DOI: 10.1056/NEJM197606102942401. View

16.

Finkelstein R, Vasil M, Jones J, Anderson R, Barnard T . Clinical cholera caused by enterotoxigenic Escherichia coli. J Clin Microbiol. 1976; 3(3):382-4. PMC: 274305. DOI: 10.1128/jcm.3.3.382-384.1976. View

17.

ORSKOV F, ORSKOV I, Evans Jr D, Sack R, Sack D, Wadstrom T . Special Escherichia coli serotypes among enterotoxigenic strains from diarrhoea in adults and children. Med Microbiol Immunol. 1976; 162(2):73-80. DOI: 10.1007/BF02121318. View

18.

Ryder R, Wachsmuth I, Buxton A, Evans D, DuPont H, Mason E . Infantile diarrhea produced by heat-stable enterotoxigenic Escherichia coli. N Engl J Med. 1976; 295(16):849-53. DOI: 10.1056/NEJM197610142951601. View

19.

GROSS R, Rowe B, Henderson A, Byatt M, MACLAURIN J . A NEW Escherichia coli O-group, O159, associated with outbreaks of enteritis in infants. Scand J Infect Dis. 1976; 8(3):195-8. DOI: 10.3109/inf.1976.8.issue-3.14. View

20.

Rowe B, Scotland S, GROSS R . Enterotoxigenic Escherichia coli causing infantile enteritis in Britain. Lancet. 1977; 1(8002):90-1. DOI: 10.1016/s0140-6736(77)91099-6. View