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Primary Immunodeficiency Disorders in Sweden: Cases Among Children, 1974-1979

Overview
Journal J Clin Immunol
Publisher Springer
Specialty Allergy & Immunology
Date 1982 Apr 1
PMID 6978347
Citations 42
Authors
A Fasth
Affiliations
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Abstract

A nationwide survey of symptomatic primary immunodeficiency disorders in children in Sweden during the 6-year period 1974-1979 resulted in 201 reported cases. The reported data for 174 children were analyzed. Antibody deficiencies were the most frequent (45.0%), followed by phagocytic disorders (22.0%) and combined T- and B-cell disorders (20.8%). Thirty-two children (18.4%) died, with the highest mortality for combined T- and B-cell defects. The sex ratio for all disorders was 2:1 for boys:girls. Neutropenia was significantly more common in the northern part of Sweden.

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