Crystalline Arrays of Membrane-bound Acetylcholine Receptor

Overview

Journal Proc Natl Acad Sci U S A

Specialty Science

Date 1981 Jun 1

PMID 6943572

Citations 26

Authors

J Kistler

R M Stroud

Affiliations

Soon will be listed here.

Abstract

Electron micrographs of tubular structures with a crystalline arrangement of membrane-bound acetylcholine receptor oligomers have been analyzed by digital image reconstruction. The receptor molecules are oriented synaptic side out, and in projection they appear to be asymmetric and have a defined orientation. All four subunits are contained in the oligomers as demonstrated by immunoelectron microscopy; these structures therefore appear to be suitable for subunit localization in the oligomer.

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