Nucleotide Sequence Homology at 12 Intron--exon Junctions in the Chick Ovalbumin Gene

Overview

Journal Nature

Specialty Science

Date 1978 Oct 12

PMID 692731

Citations 40

Authors

J F Catterall

B W OMalley

M A ROBERTSON

R Staden

Y Tanaka

G G Brownlee

Affiliations

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Abstract

A short partial sequence homology is present at all intron-exon junctions, or splice points, in the chick ovalbumin gene; it is probably a signal for a splicing enzyme. The significance of the junction sequences for splicing is discussed. We find no evidence of strong Watson-Crick base pairing between adjacent junctions.

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