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Synergism Between Vancomycin and Gentamicin or Tobramycin for Methicillin-susceptible and Methicillin-resistant Staphylococcus Aureus Strains

Overview
Specialty Pharmacology
Date 1982 Nov 1
PMID 6924825
Citations 26
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Abstract

By the time-kill curve method, the combinations of vancomycin-gentamicin and vancomycin-tobramycin were shown to be synergistic against a majority of methicillin-susceptible and -resistant strains of Staphylococcus aureus.

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References
1.
Watanakunakorm C, Glotzbecker C . Enhancement of the effects of anti-staphylococcal antibiotics by aminoglycosides. Antimicrob Agents Chemother. 1974; 6(6):802-6. PMC: 444739. DOI: 10.1128/AAC.6.6.802. View

2.
Massanari R, Donta S . The efficacy of rifampin as adjunctive therapy in selected cases of staphylococcal endocarditis. Chest. 1978; 73(3):371-5. DOI: 10.1378/chest.73.3.371. View

3.
Tuazon C, Lin M, Sheagren J . In vitro activity of rifampin alone and in combination with nafcillin and Vancomycin against pathogenic strains of Staphylococcus aureus. Antimicrob Agents Chemother. 1978; 13(5):759-61. PMC: 352328. DOI: 10.1128/AAC.13.5.759. View

4.
Faville Jr R, Zaske D, Kaplan E, Crossley K, Sabath L, Quie P . Staphylococcus aureus endocarditis. Combined therapy with vancomycin and rifampin. JAMA. 1978; 240(18):1963-5. DOI: 10.1001/jama.240.18.1963. View

5.
Watanakunakorn C . Antibiotic-tolerant Staphylococcus aureus. J Antimicrob Chemother. 1978; 4(6):561-8. DOI: 10.1093/jac/4.6.561. View