Concanavalin A Receptors and Capping in Control and Activated Macrophages

Overview

Journal Histochem J

Specialty Biochemistry

Date 1983 Jan 1

PMID 6833005

Citations 2

Authors

K Donaldson

J M Davis

K JAMES

Affiliations

Soon will be listed here.

Abstract

Macrophages activated in vivo with Corynebacterium parvum and asbestos showed an increased sub-population of cells which capped spontaneously on incubation with fluoresceinated Concanavalin A compared to saline-induced control macrophages. This capping was unaffected by colchicine but was inhibited by cytochalasin B. The spontaneous capping of activated macrophages did not appear to be directly related to the total number of Concanavalin A receptors as measured by specific 125I-labelled Concanavalin A binding to activated and control macrophages. Capping also did not appear to be related to the position of Concanavalin A receptors as judged by trypsin accessibility of bound 125I-labelled Concanavalin A.

Citing Articles

Chemiluminescence of asbestos-activated macrophages.

Donaldson K, Cullen R Br J Exp Pathol. 1984; 65(1):81-90.

PMID: 6320857 PMC: 2040938.

Interactions of asbestos-activated macrophages with an experimental fibrosarcoma.

Donaldson K, Davis J, Ewing A, JAMES K Environ Health Perspect. 1983; 51:97-101.

PMID: 6315388 PMC: 1569285. DOI: 10.1289/ehp.835197.

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