Sensitivity of Gonococci to Rosoxacin Compared with That of Penicillin, Cefuroxime and Tetracycline

Overview

Journal J Antimicrob Chemother

Publisher Oxford University Press

Specialty Infectious Diseases

Date 1981 Apr 1

PMID 6788746

Citations 5

Authors

A D Seth

Affiliations

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Abstract

The in vitro activity of rosoxacin, a pyridyl quinolone derivative against Neisseria gonorrhoeae is compared with that of penicillin, cefuroxime and tetracycline. Three groups of gonococci comprising of beta-lactamase-positive and negative strains and gonococci with high penicillin MICs are studied. Rosoxacin was the most active against the entire spectrum of gonococci tested in vitro and its activity is not affected by the production of beta-lactamase by some gonococci.

Citing Articles

In vitro susceptibility and cross-resistance of South African isolates of Neisseria gonorrhoeae to 14 antimicrobial agents.

Liebowitz L, Ballard R, Koornhof H Antimicrob Agents Chemother. 1982; 22(4):598-603.

PMID: 6817704 PMC: 183799. DOI: 10.1128/AAC.22.4.598.

Quinolone derivative, flumequine, as short-term treatment for gonorrhoea.

Svindland H, Svarva P, Maeland J Br J Vener Dis. 1982; 58(5):317-20.

PMID: 6812849 PMC: 1046084. DOI: 10.1136/sti.58.5.317.

Influence of inoculum size on comparative susceptibilities of penicillinase-positive and -negative Neisseria gonorrhoeae to 31 antimicrobial agents.

Hall W, Opfer B Antimicrob Agents Chemother. 1984; 26(2):192-5.

PMID: 6435514 PMC: 284117. DOI: 10.1128/AAC.26.2.192.

Treatment of uncomplicated gonorrhoea with rosoxacin (acrosoxacin).

Lim K, Rajan V, Giam Y, Lui E, Sng E, Yeo K Br J Vener Dis. 1984; 60(3):157-60.

PMID: 6428698 PMC: 1046290. DOI: 10.1136/sti.60.3.157.

Rosoxacin in the treatment of uncomplicated gonorrhoea in men.

Panikabutra K, Ariyarit C, Chitwarakorn A, Saensanoh C Br J Vener Dis. 1984; 60(4):231-4.

PMID: 6234966 PMC: 1046315. DOI: 10.1136/sti.60.4.231.