Effect of Environment on Sensitivity of Neisseria Gonorrhoeae to Pseudomonas Aeruginosa Bacteriocins

Overview

Journal Infect Immun

Publisher American Society for Microbiology

Specialty Allergy & Immunology

Date 1980 Aug 1

PMID 6783533

Citations 2

Authors

D C Stein

B H Hebeler

F E Young

Affiliations

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Abstract

The effect of environmental variation on the susceptibility of Neisseria gonorrhoeae to pyocin produced by Pseudomonas aeruginosa was examined. Susceptibility to at least one pyocin was demonstrated in strains of N. gonorrhoeae (99%), N. meningitidis (35%), and N. lactamica (47%). The degree of sensitivity to pyocin displayed by N. gonorrhoeae was affected by varying the pH of the growth environment. Gonococcal strains were more sensitive to growth inhibition by pyocins at an alkaline pH and less sensitive to growth inhibition at an acid pH. Inhibitory titers fluctuated during nonselective subculture of fresh clinical isolates. There was no apparent correlation between auxotype and sensitivity to pyocin. Also, no relationship between colony morphology and pyocin sensitivity was seen.

Citing Articles

Interaction with lectins and differential wheat germ agglutinin binding of pyocin 103-sensitive and -resistant Neisseria gonorrhoeae.

Connelly M, Stein D, Young F, Morse S, Allen P J Bacteriol. 1981; 148(3):796-803.

PMID: 6796562 PMC: 216277. DOI: 10.1128/jb.148.3.796-803.1981.

Autoplaquing in Neisseria gonorrhoeae.

Campbell L, SHORT H, Young F, Clark V J Bacteriol. 1985; 164(1):461-5.

PMID: 3930471 PMC: 214266. DOI: 10.1128/jb.164.1.461-465.1985.

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