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Antibiotic Sensitivities of Gonococci Isolated in Rotterdam and Results of Treatment with Cefuroxime

Overview
Journal Br J Vener Dis
Specialty Infectious Diseases
Date 1980 Aug 1
PMID 6775767
Citations 13
Authors
K C Nayyar
M F Michel
E Stolz
Affiliations
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Abstract

In a study of the efficacy of cefuroxime in the treatment of 278 cases of acute gonorrhoea (including rectal and pharyngeal infections and infections due to penicillinase-producing Neisseria gonorrhoeae), high cure rates were found for both male (98.8%) and female patients (98.6%). Disadvantages of this treatment are its high cost and the relatively high proportion of patients who develop postgonococcal urethritis.

Citing Articles

Penicillin sensitivities of gonoccocci, in 1977-80 from a peripheral health district, and their clinical correlation.

Rahman M Postgrad Med J. 1982; 58(676):77-9.

PMID: 6808472 PMC: 2426295. DOI: 10.1136/pgmj.58.676.77.

Penicillinase-producing Neisseria gonorrhoeae in Great Britain, 1977-81: alarming increase in incidence and recent development of endemic transmission.

McCutchan J, Adler M, BERRIE J Br Med J (Clin Res Ed). 1982; 285(6338):337-40.

PMID: 6807472 PMC: 1498969. DOI: 10.1136/bmj.285.6338.337.

Penicillinase-producing Neisseria gonorrhoeae in Riyadh, Saudi Arabia.

Chowdhury M, Pareek S, Mahgoub E Br J Vener Dis. 1981; 57(4):256-8.

PMID: 6791760 PMC: 1045936. DOI: 10.1136/sti.57.4.256.

Gonorrhoea: a continuing problem in the 1980s.

Thin R Br J Vener Dis. 1980; 56(4):193.

PMID: 6775762 PMC: 1045775. DOI: 10.1136/sti.56.4.193.

Susceptibility of Neisseria gonorrhoeae to cefotaxime: in vitro studies and treatment results.

Neubert U, Korting H, Ruckdeschel G Arch Dermatol Res. 1982; 274(3-4):321-6.

PMID: 6299208 DOI: 10.1007/BF00403736.

References
1.
Fowler W, Rahim G . Cefuroxime and post-gonococcal urethritis. Proc R Soc Med. 2010; 70(Suppl 9):131-3. PMC: 1543263. View
2.
Berg S, Kilpatrick M, HARRISON W, McCutchan J . Cefoxitin as a single-dose treatment for urethritis caused by penicillinase-producing Neisseria gonorrhoeae. N Engl J Med. 1979; 301(10):509-11. DOI: 10.1056/NEJM197909063011001. View
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Phillips C, Aller R, Cohen S . Penicillinase-producing Neisseria gonorrhoeae. Lancet. 1976; 2(7992):960. DOI: 10.1016/s0140-6736(76)90918-1. View
4.
Stolz E, Michel M, Schuller J, de Koning G . Sensitivity of gonococcus strains isolated in Rotterdam to epicillin, ampicillin, penicillin and tetracycline. Dermatologica. 1978; 157(3):158-63. DOI: 10.1159/000250823. View
5.
Stolz E, Zwart H, Michel M . Sensitivity to ampicillin, penicillin, and tetracyline of gonococci in Rotterdam. Br J Vener Dis. 1974; 50(3):202-7. PMC: 1045016. DOI: 10.1136/sti.50.3.202. View