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Structural Variability of TRNA: Small-angle X-ray Scattering of the Yeast TRNAphe-Escherichia Coli TRNAGlu2 Complex

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Specialty Science
Date 1982 Oct 1
PMID 6764532
Citations 6
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Abstract

The structure of the complex formed in solution between yeast tRNAPhe and Escherichia coli tRNAGlu2 has been studied by small-angle x-ray scattering. The complex has a radius of gyration of 4.0 nm and an electron-pair distance distribution that is incompatible with a model composed to two tRNAs joined at their complementary anticodons and exhibiting the L shape seen in the crystal. Instead a model in which the two tRNAs, still bound via the anticodons, assume a conformation with the acceptor arms folded toward the anticodon arms agrees with the observed scattering curves.

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