Permeability and Susceptibility of Escherichia Coli to Beta-lactam Compounds

Overview

Journal Antimicrob Agents Chemother

Publisher American Society for Microbiology

Specialty Pharmacology

Date 1981 Feb 1

PMID 6751219

Citations 5

Authors

D Clark

Affiliations

Soon will be listed here.

Abstract

In general, the susceptibility of envelope mutants of Escherichia coli to beta-lactam compounds correlates well with the permeability of these antibiotics through the outer membrane. However, several mutants were isolated which, although apparently freely permeable to penicillins, showed only marginal increases in susceptibility to these agents.

Citing Articles

Target for bacteriostatic and bactericidal activities of beta-lactam antibiotics against Escherichia coli resides in different penicillin-binding proteins.

Satta G, Cornaglia G, Mazzariol A, Golini G, Valisena S, Fontana R Antimicrob Agents Chemother. 1995; 39(4):812-8.

PMID: 7785976 PMC: 162634. DOI: 10.1128/AAC.39.4.812.

In vitro antibacterial activity and beta-lactamase stability of E-0702, a new cephalosporin.

Neu H, Labthavikul P Antimicrob Agents Chemother. 1983; 24(3):313-20.

PMID: 6605718 PMC: 185318. DOI: 10.1128/AAC.24.3.313.

Comparative in vitro activity and beta-lactamase stability of FR 17027, a new orally active cephalosporin.

Neu H, Chin N, Labthavikul P Antimicrob Agents Chemother. 1984; 26(2):174-80.

PMID: 6333207 PMC: 284114. DOI: 10.1128/AAC.26.2.174.

Evaluation of bactericidal activity of cefotaxime and other beta-lactams by a novel method.

Satta G, Cornaglia G, Canepari P, Pompei R Drugs. 1988; 35 Suppl 2:35-40.

PMID: 3293978 DOI: 10.2165/00003495-198800352-00009.

Diffusion of meropenem and imipenem through the outer membrane of Escherichia coli K-12 and correlation with their antibacterial activities.

Cornaglia G, Guan L, Fontana R, Satta G Antimicrob Agents Chemother. 1992; 36(9):1902-8.

PMID: 1416880 PMC: 192207. DOI: 10.1128/AAC.36.9.1902.

References

Braun V . Covalent lipoprotein from the outer membrane of Escherichia coli. Biochim Biophys Acta. 1975; 415(3):335-77. DOI: 10.1016/0304-4157(75)90013-1. View

Richmond M, Clark D, Wotton S . Indirect method for assessing the penetration of beta-lactamase-nonsusceptible penicillins and cephalosporins in Escherichia coli strains. Antimicrob Agents Chemother. 1976; 10(2):215-8. PMC: 429723. DOI: 10.1128/AAC.10.2.215. View

Beard J, Connolly J . Detection of a protein, similar to the sex pilus subunit, in the outer membrane of Escherichia coli cells carrying a derepressed F-like R factor. J Bacteriol. 1975; 122(1):59-65. PMC: 235639. DOI: 10.1128/jb.122.1.59-65.1975. View

DiRienzo J, Nakamura K, Inouye M . The outer membrane proteins of Gram-negative bacteria: biosynthesis, assembly, and functions. Annu Rev Biochem. 1978; 47:481-532. DOI: 10.1146/annurev.bi.47.070178.002405. View

Clark D, Beard J . Altered phospholipid composition in mutants of Escherichia coli sensitive or resistant to organic solvents. J Gen Microbiol. 1979; 113(2):267-74. DOI: 10.1099/00221287-113-2-267. View