Effect of Temocillin in Combination with Other Beta-lactam Antibiotics

Overview

Journal Antimicrob Agents Chemother

Publisher American Society for Microbiology

Specialty Pharmacology

Date 1984 Jan 1

PMID 6703679

Citations 9

Authors

L Verbist

J Verhaegen

Affiliations

Soon will be listed here.

Abstract

The antibacterial interactions of temocillin with other beta-lactams were tested by checkerboard combination in Mueller-Hinton agar against 146 strains of members of the family Enterobacteriaceae, 35 Pseudomonas aeruginosa strains, and 35 Staphylococcus aureus strains. Most combinations showed a moderate degree of synergism. In only one Klebsiella strain was minor antagonism observed between temocillin and ampicillin.

Citing Articles

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Assessing Clinical Potential of Old Antibiotics against Severe Infections by Multi-Drug-Resistant Gram-Negative Bacteria Using In Silico Modelling.

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Temocillin: Applications in Antimicrobial Stewardship as a Potential Carbapenem-Sparing Antibiotic.

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Amoxicillin plus temocillin as an alternative empiric therapy for the treatment of severe hospital-acquired pneumonia: results from a retrospective audit.

Habayeb H, Sajin B, Patel K, Grundy C, Al-Dujaili A, Van de Velde S Eur J Clin Microbiol Infect Dis. 2015; 34(8):1693-9.

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In vitro activity of omeprazole in combination with several antimicrobial agents against clinical isolates of Helicobacter pylori.

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References

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