Rat Mononuclear Cells and Neutrophils Are More Effective Than Eosinophils in Antibody-mediated Stage-specific Killing of Trichinella Spiralis in Vitro

Overview

Journal Z Parasitenkd

Specialty Parasitology

Date 1983 Jan 1

PMID 6659655

Citations 1

Authors

E J Ruitenberg

J Buys

J S Teppema

A Elgersma

Affiliations

Soon will be listed here.

Abstract

The capacity of non-infected rat total, eosinophil-enriched and eosinophil-depleted fractions of peritoneal exudate and bone marrow cells to adhere to and kill Trichinella spiralis newborn larvae with immune rat serum has been studied in vitro. The eosinophil-depleted peritoneal exudate cell fraction contained mainly mononuclear cells, whereas the corresponding bone marrow cell fraction consisted of a considerable number of neutrophils. All cell types either originating from the peritoneal cavity or the bone marrow, showed adherence and killing properties to the Trichinella newborn larvae. It was concluded that mononuclear cells and neutrophils are capable of and more effective than eosinophils in stage-specific killing of Trichinella in vitro.

Citing Articles

Effects of macrophage activity on the antibody-dependent cytotoxicity against Trichinella spiralis newborn larvae: an in vitro cytotoxicity and ultrastructural study.

ANTEUNIS A, Astesano A, Ruitenberg E Z Parasitenkd. 1985; 71(2):249-57.

PMID: 3887792 DOI: 10.1007/BF00926275.

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