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Increased Dihydrofolate Reductase, Double Minutes and Increased Nucleolar Activation in Methotrexate-resistant HeLa Cells

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Journal Experientia
Specialty Science
Date 1983 Dec 15
PMID 6653732
Citations 3
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References
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GEORGE D, Francke U . Homogeneously staining chromosome regions and double minutes in a mouse adrenocortical tumor cell line. Cytogenet Cell Genet. 1980; 28(4):217-26. DOI: 10.1159/000131535. View

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Heintz N, Hamlin J . An amplified chromosomal sequence that includes the gene for dihydrofolate reductase initiates replication within specific restriction fragments. Proc Natl Acad Sci U S A. 1982; 79(13):4083-7. PMC: 346581. DOI: 10.1073/pnas.79.13.4083. View

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Caizzi R, Bostock C . Gene amplification in methotrexate-resistant mouse cells. IV. Different DNA sequences are amplified in different resistant lines. Nucleic Acids Res. 1982; 10(21):6597-618. PMC: 326952. DOI: 10.1093/nar/10.21.6597. View

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Delinassios J, Pandis N, Margaronis M, Kottaridis S . Double minutes in fibroblast-like cells isolated from human tumors. Experientia. 1981; 37(6):569-70. DOI: 10.1007/BF01990054. View

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Delinassios J, Voloudakis-Baltatzis I, Kottaridis S, Garas J . Nonrandom association of acrocentric chromosomes in human epithelial cells. Experientia. 1981; 37(5):476-8. DOI: 10.1007/BF01986144. View