The Effect of Cimetidine on Tolbutamide Kinetics

Overview

Journal Br J Clin Pharmacol

Specialty Pharmacology

Date 1983 Oct 1

PMID 6626438

Citations 13

Authors

N G Dey

C M Castleden

J Ward

J Cornhill

A McBurney

Affiliations

Soon will be listed here.

Abstract

Although possible on theoretical grounds, no interaction between cimetidine and tolbutamide could be demonstrated in ten healthy volunteers. The plasma tolbutamide concentrations over 12 h following 0.5 g orally were essentially the same before and after 1 and 7 days cimetidine (400 mg twice daily).

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References

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