Analysis of Heart Rate Variations in Patients with Multiple Sclerosis. A Simple Measure of Autonomic Nervous Disturbances Using an Ordinary ECG

Overview

Journal J Neurol Neurosurg Psychiatry

Publisher BMJ Publishing Group

Specialties Neurology
Neurosurgery
Psychiatry

Date 1978 May 1

PMID 660203

Citations 19

Authors

B Neubauer

H J Gundersen

Affiliations

Soon will be listed here.

Abstract

A simple method requiring only an ordinary ECG apparatus and a ruler has shown a hitherto unknown abnormality of the autonomic nervous sysyem in patients with multiple sclerosis. The main findings were that both long-term and short-term variations in heart rate were reduced in patients wirh multiple sclerosis. The reduction was comparable with that observed in other patients with autonomic abnormalities-for example, long-term diabetics-but in addition patients with multiple sclerosis presented unexpected large shifts in pulse rate levels, lasting from a few to 10 or 20 beats.

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References

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Gundersen H, Neubauer B . A long-term diabetic autonomic nervous abnormality. Reduced variations in resting heart rate measured by a simple and sensitive method. Diabetologia. 1977; 13(2):137-40. DOI: 10.1007/BF00745141. View