Computer Programs Used to Aid in the Selection of DNA Hybridization Probes
Overview
Overview
Journal
Nucleic Acids Res
Publisher
Oxford University Press
Specialty
Biochemistry
Date
1984 Jan 11
PMID
6546442
Citations
1
Authors
Authors
Affiliations
Affiliations
Soon will be listed here.
Abstract
This paper describes a package of three programs which used together aid in selecting the best possible sequence to be used as a DNA hybridization probe. This system searches an amino acid sequence for four adjacent amino acids with the fewest possible corresponding mRNA sequences, calculates their probability of occurrence, and locates the positions of wobbles and mismatches between the DNA hybridization probe and the possible mRNA sequences.
Citing Articles
Dubnick M, Lewis L, Mount D Nucleic Acids Res. 1988; 16(5):1703-14.
PMID: 3353219 PMC: 338165. DOI: 10.1093/nar/16.5.1703.
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