Role of Radiologic Imaging in Management Planning of Giant Cell Tumor of Bone

Overview

Journal Skeletal Radiol

Specialties Orthopedics
Radiology

Date 1984 Jan 1

PMID 6484605

Citations 16

Authors

E Levine

A A de Smet

J R Neff

Affiliations

Soon will be listed here.

Abstract

The radiologic studies of 24 patients with giant cell tumors were evaluated with respect to their ability to determine tumor extent and to influence management. Computed tomography (CT) was the most accurate method for detecting soft tissue tumor extension, and conventional tomography was the best technique for evaluating penetration of subarticular cortical bone. Detection of these findings led to performance of en bloc tumor resection rather than curettage and grafting in patients with lower extremity tumors. Arthrotomography was helpful in some instances in detecting cartilage and joint invasion by tumor, joint invasion being an indication for extra-articular rather than transarticular tumor resection. Scintigraphy was not as accurate as conventional tomography or CT in determining intraosseous tumor extent because of increased tracer uptake beyond the true tumor limits in several cases. Angiography has been largely replaced by CT in evaluating giant cell tumors.

Citing Articles

Comparative analysis of aggressiveness in giant cell tumor of bone between upper and lower extremities: A systematic review and meta-analysis.

Saputra R, Kusuma D, Kaldani F, Fahmi K J Bone Oncol. 2025; 51:100663.

PMID: 40028631 PMC: 11871493. DOI: 10.1016/j.jbo.2025.100663.

Images of giant cell tumor and chondroblastoma around the knee: retrospective analysis of 99 cases.

Ma J, Wu Y, Wen J, Zhong Z, Yu B, Liu C Quant Imaging Med Surg. 2023; 13(2):787-800.

PMID: 36819259 PMC: 9929425. DOI: 10.21037/qims-22-616.

Clinical Scenario and Imaging with Illustrations of Giant Cell Tumor of Bone: A Retrospective Analysis.

Ali N, Shah A, Rakshan I Arch Bone Jt Surg. 2022; 10(1):60-66.

PMID: 35291246 PMC: 8889423. DOI: 10.22038/ABJS.2021.50922.2522.

Carpal giant cell tumor.

Arunachalam V, Saran S Sudan J Paediatr. 2020; 20(2):189-191.

PMID: 32817742 PMC: 7423310. DOI: 10.24911/SJP.106-1585826722.

Giant cell tumor of bone revisited.

Mavrogenis A, Igoumenou V, Megaloikonomos P, Panagopoulos G, Papagelopoulos P, Soucacos P SICOT J. 2017; 3:54.

PMID: 28905737 PMC: 5598212. DOI: 10.1051/sicotj/2017041.

References

GOLDENBERG R, Campbell C, Bonfiglio M . Giant-cell tumor of bone. An analysis of two hundred and eighteen cases. J Bone Joint Surg Am. 1970; 52(4):619-64. View

Mnaymneh W, Dudley H, MNAYMNEH L . GIANT-CELL TUMOR OF BONE. AN ANALYSIS AND FOLLOW-UP STUDY OF THE FORTY-ONE CASES OBSERVED AT THE MASSACHUSETTS GENERAL HOSPITAL BETWEEN 1925 AND 1960. J Bone Joint Surg Am. 1964; 46:63-75. View

Karakousis C, Park J, Fleminger R, Friedman M . Chordomas: diagnosis and management. Am Surg. 1981; 47(11):497-501. View

Hudson T, ENNEKING W, Hawkins Jr I . The value of angiography in planning surgical treatment of bone tumors. Radiology. 1981; 138(2):283-92. DOI: 10.1148/radiology.138.2.6935699. View

ENNEKING W, Spanier S, Goodman M . A system for the surgical staging of musculoskeletal sarcoma. Clin Orthop Relat Res. 1980; (153):106-20. View

Simon M, Kirchner P . Scintigraphic evaluation of primary bone tumors. Comparison of technetium-99m phosphonate and gallium citrate imaging. J Bone Joint Surg Am. 1980; 62(5):758-64. View

Lundstrom B, Lorentzon R, Larsson S, Boquist L . Angiography in giant-cell tumours of bone. Acta Radiol Diagn (Stockh). 1977; 18(5):541-53. DOI: 10.1177/028418517701800506. View

Smith G, Winquist R, Allan N, Northrop C . Subtle transchondral fractures of the talar dome: a radiological perspective. Radiology. 1977; 124(3):667-73. DOI: 10.1148/124.3.667. View

Larsson S . Removal of the third thoracic vertebra and partial lung resection for a radioresistant giant-cell tumour of the spine. J Bone Joint Surg Br. 1979; 61-B(4):489-93. DOI: 10.1302/0301-620X.61B4.500762. View

10.

Schwimer S, Bassett L, Mancuso A, Mirra J, Dawson E . Giant cell tumor of the cervicothoracic spine. AJR Am J Roentgenol. 1981; 136(1):63-7. DOI: 10.2214/ajr.136.1.63. View

11.

de Smet A, Neff J . Knee arthrography for the preoperative evaluation of juxta-articular masses. Radiology. 1982; 143(3):663-6. DOI: 10.1148/radiology.143.3.6952524. View

12.

Prando A, deSantos L, Wallace S, Murray J . Angiography in giant-cell bone tumors. Radiology. 1979; 130(2):323-31. DOI: 10.1148/130.2.323. View

13.

Soye I, Levine E, de Smet A, Neff J . Computed tomography in the preoperative evaluation of masses arising in or near the joints of the extremities. Radiology. 1982; 143(3):727-32. DOI: 10.1148/radiology.143.3.6952525. View

14.

Seradge H . Distal ulnar translocation in the treatment of giant-cell tumors of the distal end of the radius. J Bone Joint Surg Am. 1982; 64(1):67-73. View

15.

Resnick D . Arthrography in the evaluation of arthritic disorders of the wrist. Radiology. 1974; 113(2):331-40. DOI: 10.1148/113.2.331. View

16.

Thrall J, Geslien G, Corcoron R, Johnson M . Abnormal radionuclide deposition patterns adjacent to focal skeletal lesions. Radiology. 1975; 115(3):659-63. DOI: 10.1148/15.3.659. View

17.

LAURIN S . Angiography in giant cell tumors. Radiologe. 1977; 17(3):118-23. View

18.

Smith J, Wixon D, Watson R . Giant-cell tumor of the sacrum. Clinical and radiologic features in 13 patients. J Can Assoc Radiol. 1979; 30(1):34-9. View

19.

Levine E, Lee K, Neff J, Maklad N, Robinson R, PRESTON D . Comparison of computed tomography and other imaging modalities in the evaluation of musculoskeletal tumors. Radiology. 1979; 131(2):431-7. DOI: 10.1148/131.2.431. View

20.

Hudson T, Schiebler M, Springfield D, Hawkins Jr I, ENNEKING W, Spanier S . Radiologic imaging of osteosarcoma: role in planning surgical treatment. Skeletal Radiol. 1983; 10(3):137-46. DOI: 10.1007/BF00357767. View