» Articles » PMID: 27594954

A Case of Thoracic Giant Cell Tumor of Bone and Discussion of Radiological Features and Current Management Practices

Overview
Journal Radiol Case Rep
Publisher Elsevier
Specialty Radiology
Date 2016 Sep 6
PMID 27594954
Citations 4
Authors
Affiliations
Soon will be listed here.
Abstract

Giant cell tumor of bone (GCTB) is a rare condition with distinct radiological features that aid diagnosis. We present the case of an adult female patient, with locally invasive GCTB and review important radiological and management principles. Specific radiological features include locally aggressive, lytic radiolucent lesions, which can demonstrate cortical thinning and expansile remodeling of bone and typically involve the epiphysis and metaphysis. Management is primarily surgical, and denosumab has a role in the advanced setting.

Citing Articles

L5 giant cell tumor in 28-year-old female.

Baskoro W, Pratama M, Fauziah E, Rusidi H, Kameswari B Surg Neurol Int. 2024; 15:436.

PMID: 39640347 PMC: 11618681. DOI: 10.25259/SNI_533_2024.


Giant cell tumor of the thoracic spine causing acute paraplegia-a case report.

Lucasti C, Patel D, Hawayek B, Maraschiello M, Kowalski J J Spine Surg. 2021; 7(2):208-213.

PMID: 34296034 PMC: 8261563. DOI: 10.21037/jss-20-652.


Changing care pathways and between-center practice variations in intensive care for traumatic brain injury across Europe: a CENTER-TBI analysis.

Huijben J, Wiegers E, Lingsma H, Citerio G, Maas A, Menon D Intensive Care Med. 2020; 46(5):995-1004.

PMID: 32100061 PMC: 7210239. DOI: 10.1007/s00134-020-05965-z.


Primary thoracic giant cell tumor of bone sensitive to steroids.

Yang H, Im G, Nielsen G, Kheterpal A, Schwab J Skeletal Radiol. 2018; 47(10):1431-1435.

PMID: 29502130 DOI: 10.1007/s00256-018-2911-y.

References
1.
Arnold R, van Holsbeeck M, Mayer T, Mott M, Koch S . Best cases from the AFIP: Necrotic giant cell tumor of bone manifesting with pathologic fracture. Radiographics. 2011; 31(1):93-8. DOI: 10.1148/rg.311105048. View

2.
Tse L, Wong K, Kumta S, Huang L, Chow T, Griffith J . Bisphosphonates reduce local recurrence in extremity giant cell tumor of bone: a case-control study. Bone. 2007; 42(1):68-73. DOI: 10.1016/j.bone.2007.08.038. View

3.
Wang C, Lou J, Liao J, Ding X, Du L, Lu Y . Recurrence in giant cell tumour of bone: imaging features and risk factors. Radiol Med. 2012; 118(3):456-64. DOI: 10.1007/s11547-012-0860-4. View

4.
Campanacci M, Baldini N, Boriani S, Sudanese A . Giant-cell tumor of bone. J Bone Joint Surg Am. 1987; 69(1):106-14. View

5.
Chakarun C, Forrester D, Gottsegen C, Patel D, White E, Matcuk Jr G . Giant cell tumor of bone: review, mimics, and new developments in treatment. Radiographics. 2013; 33(1):197-211. DOI: 10.1148/rg.331125089. View