A Case of Thoracic Giant Cell Tumor of Bone and Discussion of Radiological Features and Current Management Practices
Overview
Affiliations
Giant cell tumor of bone (GCTB) is a rare condition with distinct radiological features that aid diagnosis. We present the case of an adult female patient, with locally invasive GCTB and review important radiological and management principles. Specific radiological features include locally aggressive, lytic radiolucent lesions, which can demonstrate cortical thinning and expansile remodeling of bone and typically involve the epiphysis and metaphysis. Management is primarily surgical, and denosumab has a role in the advanced setting.
L5 giant cell tumor in 28-year-old female.
Baskoro W, Pratama M, Fauziah E, Rusidi H, Kameswari B Surg Neurol Int. 2024; 15:436.
PMID: 39640347 PMC: 11618681. DOI: 10.25259/SNI_533_2024.
Giant cell tumor of the thoracic spine causing acute paraplegia-a case report.
Lucasti C, Patel D, Hawayek B, Maraschiello M, Kowalski J J Spine Surg. 2021; 7(2):208-213.
PMID: 34296034 PMC: 8261563. DOI: 10.21037/jss-20-652.
Huijben J, Wiegers E, Lingsma H, Citerio G, Maas A, Menon D Intensive Care Med. 2020; 46(5):995-1004.
PMID: 32100061 PMC: 7210239. DOI: 10.1007/s00134-020-05965-z.
Primary thoracic giant cell tumor of bone sensitive to steroids.
Yang H, Im G, Nielsen G, Kheterpal A, Schwab J Skeletal Radiol. 2018; 47(10):1431-1435.
PMID: 29502130 DOI: 10.1007/s00256-018-2911-y.