Serum Concentrations of PRL, GH, LH, FSH, TSH and Cortisol After Single Administration to Man of a New Synthetic Narcotic Analgesic Butorphanol

Overview

Journal Eur J Clin Pharmacol

Specialty Pharmacology

Date 1984 Jan 1

PMID 6432552

Citations 1

Authors

E Rolandi

R Franceschini

A Marabini

V Messina

T Barreca

Affiliations

Soon will be listed here.

Abstract

The i.m. administration to 6 healthy adult male volunteers of 2 mg butorphanol, a potent synthetic opiate analgesic, resulted in a significant rise in serum PRL level, without affecting GH, LH, FSH, TSH or cortisol secretion. These effects indicate that in man butorphanol exerts an opiate agonist rather than an opiate antagonist effect at the hypothalamic and/or pituitary level.

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