Effects of Two Analgesic Opiates (methadone and Pentazocine) on the Serum Prolactin Levels in Breast Cancer

Overview

Journal Acta Endocrinol (Copenh)

Specialty Endocrinology

Date 1978 Jul 1

PMID 581016

Citations 4

Authors

E Rolandi

T Barreca

Affiliations

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Abstract

In 18 female patients affected by advanced breast cancer, the serum prolactin (PRL) levels have been determined under basal conditions and after the administration of analgesic opiates such as methadone and pentazocine. A significant increase of prolactin serum values was found after the use of both drugs. This finding is considered to be of clinical importance.

Citing Articles

Changes in nalorphine-induced hyperprolactinaemia after bromocriptine or sulpiride administration.

Barreca T, Magnani G, Sannia A, Rolandi E Eur J Clin Pharmacol. 1982; 22(4):375-6.

PMID: 7106173 DOI: 10.1007/BF00548408.

Hormonal changes induced by a partial opiate antagonist, nalorphine. Evaluation of PRL, GH, TSH, LH, FSH and cortisol secretion.

Rolandi E, Magnani G, Sannia A, Barreca T Eur J Clin Pharmacol. 1981; 21(1):23-5.

PMID: 6800826 DOI: 10.1007/BF00609583.

Serum concentrations of PRL, GH, LH, FSH, TSH and cortisol after single administration to man of a new synthetic narcotic analgesic butorphanol.

Rolandi E, Franceschini R, Marabini A, Messina V, Barreca T Eur J Clin Pharmacol. 1984; 26(5):563-5.

PMID: 6432552 DOI: 10.1007/BF00543485.

Drug-induced changes in prolactin secretion. Clinical implications.

Hell K, Wernze H Med Toxicol Adverse Drug Exp. 1988; 3(6):463-98.

PMID: 3063922 DOI: 10.1007/BF03259897.