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Drosophila Melanogaster Mitochondrial DNA, a Novel Organization and Genetic Code

Overview
Journal Nature
Specialty Science
Date 1983 Jul 21
PMID 6408489
Citations 100
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Abstract

The sequence of a 4,869 base-pair fragment of Drosophila melanogaster mitochondrial DNA is presented. It contains genes for cytochrome oxidase subunits I, II and III, ATPase subunit 6 and six tRNAs together with two unassigned reading frames. The gene organization differs from that of mammalian mitochondrial DNAs. Evidence is provided for a genetic code in which AGA codes for serine and the quadruplet ATAA is used in initiation of translation.

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