» Articles » PMID: 6370430

Structural Studies of the O-specific Side Chain of the Lipopolysaccharide from Escherichia Coli O:7

Overview
Journal Carbohydr Res
Publisher Elsevier
Date 1984 Mar 15
PMID 6370430
Citations 20
Authors
Affiliations
Soon will be listed here.
Abstract

The structure of the O-specific side-chain of the lipopolysaccharide from Escherichia coli O:7 has been investigated, using n.m.r. spectroscopy, methylation analysis, partial hydrolysis, and Smith degradation as the principal methods. It is concluded that the polysaccharide is constructed of repeating pentasaccharide units having the structure (formula; see text) where D-QuipNAc stands for 4-acetamido-4,6-dideoxy-D-glucopyranose. The 13C-n.m.r. spectrum of the polysaccharide has been interpreted completely.

Citing Articles

On-demand biomanufacturing of protective conjugate vaccines.

Stark J, Jaroentomeechai T, Moeller T, Hershewe J, Warfel K, Moricz B Sci Adv. 2021; 7(6).

PMID: 33536221 PMC: 7857678. DOI: 10.1126/sciadv.abe9444.


Structure and genetics of Escherichia coli O antigens.

Liu B, Furevi A, Perepelov A, Guo X, Cao H, Wang Q FEMS Microbiol Rev. 2019; 44(6):655-683.

PMID: 31778182 PMC: 7685785. DOI: 10.1093/femsre/fuz028.


In vivo production of a novel glycoconjugate vaccine against Shigella flexneri 2a in recombinant Escherichia coli: identification of stimulating factors for in vivo glycosylation.

Kampf M, Braun M, Sirena D, Ihssen J, Thony-Meyer L, Ren Q Microb Cell Fact. 2015; 14:12.

PMID: 25612741 PMC: 4308876. DOI: 10.1186/s12934-015-0195-7.


Diversity of o-antigen repeat unit structures can account for the substantial sequence variation of wzx translocases.

Hong Y, Reeves P J Bacteriol. 2014; 196(9):1713-22.

PMID: 24532778 PMC: 3993327. DOI: 10.1128/JB.01323-13.


A UDP-HexNAc:polyprenol-P GalNAc-1-P transferase (WecP) representing a new subgroup of the enzyme family.

Merino S, Jimenez N, Molero R, Bouamama L, Regue M, Tomas J J Bacteriol. 2011; 193(8):1943-52.

PMID: 21335454 PMC: 3133024. DOI: 10.1128/JB.01441-10.