Antigenic Relationships Among Some Bovine Rotaviruses: Serum Neutralization and Cross-protection in Gnotobiotic Calves

Overview

Journal J Clin Microbiol

Specialty Microbiology

Date 1983 Aug 1

PMID 6311873

Citations 51

Authors

G N Woode

N E Kelso

T F Simpson

S K Gaul

L E Evans

L Babiuk

Affiliations

Soon will be listed here.

Abstract

A method was further developed to screen non-tissue-culture-adapted bovine rotaviruses for serotype, using a neutralization test with infectious fecal rotavirus. One of those rotaviruses (B223) which was not blocked by antiserum to the neonatal calf diarrhea virus (NCDV) serotype was then adapted to cell culture in the presence of the antiserum for two or more passages and hyperimmune antiserum to this isolate had a 60-fold-higher homologous neutralization titer than with the NCDV serotype rotavirus. Seventy-three isolates were serotyped and eight (11%) were not of the NCDV serotype (bovine rotavirus serotype I). Of these eight, five belonged to the new bovine rotavirus serotype II and three were not typed, indicating the existence of one or more further serotypes. Cross-protection studies in gnotobiotic calves showed that cross-protection only occurred between rotaviruses of the same serotype, and even a minor serotype difference was sufficient for the calves to show a lack of cross-protection. The serotypes (I and II and the three untyped isolates) also showed differences in the rate of migration in polyacrylamide gel electrophoresis of some of their RNA segments (no. 4, 6, 7, 8, 9, 10), indicating that they were of different electropherotypes.

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References

Laemmli U . Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 1970; 227(5259):680-5. DOI: 10.1038/227680a0. View

Welch A . Purification, morphology and partial characterization of a reovirus-like agent associated with neonatal calf diarrhea. Can J Comp Med. 1971; 35(3):195-202. PMC: 1319605. View

Woode G, Bridger J, Hall G, Dennis M . The isolation of a reovirus-like agent associated with diarrhoea in colostrum-deprived calves in Great Britain. Res Vet Sci. 1974; 16(1):102-5. View

Hall G, Bridger J, CHANDLER R, Woode G . Gnotobiotic piglets experimentally infected with neonatal calf diarrhoea reovirus-like agent (Rotavirus). Vet Pathol. 1976; 13(3):197-210. DOI: 10.1177/030098587601300304. View

Thouless M, Bryden A, Flewett T, Woode G, Bridger J, Snodgrass D . Serological relationships between rotaviruses from different species as studied by complement fixation and neutralization. Arch Virol. 1977; 53(4):287-94. DOI: 10.1007/BF01315627. View

Spence L, Fauvel M, Petro R, Babiuk L . Comparison of rotavirus strains by hemagglutination inhibition. Can J Microbiol. 1978; 24(4):353-62. DOI: 10.1139/m78-059. View

Flewett T, Woode G . The rotaviruses. Arch Virol. 1978; 57(1):1-23. PMC: 7087197. DOI: 10.1007/BF01315633. View

Woode G, Bew M, Dennis M . Studies on cross protection induced in calves by rotaviruses of calves, children and foals. Vet Rec. 1978; 103(2):32-4. DOI: 10.1136/vr.103.2.32. View

Derbyshire J, Woode G . Classification of rotaviruses: report from the World Health Organization/Food and Agriculture Organization Comparative Virology Program. J Am Vet Med Assoc. 1978; 173(5 Pt 2):519-21. View

10.

Eberts T, Sample R, Glick M, Ellis G . A simplified, colorimetric micromethod for xylose in serum or urine, with phloroglucinol. Clin Chem. 1979; 25(8):1440-3. View

11.

Bridger J, Brown J . Development of immunity to porcine rotavirus in piglets protected from disease by bovine colostrum. Infect Immun. 1981; 31(3):906-10. PMC: 351404. DOI: 10.1128/iai.31.3.906-910.1981. View

12.

Dyall-Smith M, HOLMES I . Gene-coding assignments of rotavirus double-stranded RNA segments 10 and 11. J Virol. 1981; 38(3):1099-103. PMC: 171252. DOI: 10.1128/JVI.38.3.1099-1103.1981. View

13.

Kalica A, Greenberg H, Wyatt R, Flores J, Sereno M, Kapikian A . Genes of human (strain Wa) and bovine (strain UK) rotaviruses that code for neutralization and subgroup antigens. Virology. 1981; 112(2):385-90. DOI: 10.1016/0042-6822(81)90285-3. View

14.

Murakami Y, Nishioka N, Hashiguchi Y, KUNIYASU C . Neutralizing patterns of anti-bovine rotavirus (Lincoln) serum against cytopathic bovine rotaviruses isolated from calves in Japan. Microbiol Immunol. 1981; 25(10):1097-100. DOI: 10.1111/j.1348-0421.1981.tb00117.x. View

15.

Woode G, Reed D, Runnels P, Herrig M, Hill H . Studies with an unclassified virus isolated from diarrheic calves. Vet Microbiol. 1982; 7(3):221-40. PMC: 7117454. DOI: 10.1016/0378-1135(82)90036-0. View

16.

Gaul S, Simpson T, Woode G, Fulton R . Antigenic relationships among some animal rotaviruses: virus neutralization in vitro and cross-protection in piglets. J Clin Microbiol. 1982; 16(3):495-503. PMC: 272397. DOI: 10.1128/jcm.16.3.495-503.1982. View