Gene Coding Assignments for Growth Restriction, Neutralization and Subgroup Specificities of the W and DS-1 Strains of Human Rotavirus

Overview

Journal J Gen Virol

Specialty Microbiology

Date 1983 Feb 1

PMID 6300286

Citations 92

Authors

H B Greenberg

J Flores

A R Kalica

R G Wyatt

R Jones

Affiliations

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Abstract

Gene coding assignments for growth restriction, neutralization and subgroup specificities were determined for two human rotavirus strains, DS-1 and W, which represent two distinct serotypes. The 4th gene segment of both viruses was associated with restriction of growth in cell culture. The 9th gene segment of W virus and 8th segment of DS-1 were associated with serotype specificity, while the 6th gene segment of W virus was associated with subgroup specificity.

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