Methylation of the Chicken Vitellogenin Gene: Influence of Estradiol Administration

Overview

Journal Nucleic Acids Res

Publisher Oxford University Press

Specialty Biochemistry

Date 1983 Mar 11

PMID 6298743

Citations 14

Authors

F C Meijlink

J N Philipsen

M Gruber

G Ab

Affiliations

Soon will be listed here.

Abstract

The degree of methylation of the chicken vitellogenin gene has been investigated. Upon induction by administration of estradiol to a rooster, methyl groups at specific sites near the 5'-end of the gene are eliminated. The process of demethylation is slower than the activation of the gene. Demethylation is therefore probably not a prerequisite to gene transcription. At least two other sites in the coding region of the gene are methylated in the liver of estrogenized roosters, but not in the liver of a laying hen, where the gene is naturally active.

Citing Articles

Chronic exposure of killifish to a highly polluted environment desensitizes estrogen-responsive reproductive and biomarker genes.

Bugel S, Bonventre J, White L, Tanguay R, Cooper K Aquat Toxicol. 2014; 152:222-31.

PMID: 24794048 PMC: 4084733. DOI: 10.1016/j.aquatox.2014.04.014.

Preferential binding of estrogen-receptor complex to a region containing the estrogen-dependent hypomethylation site preceding the chicken vitellogenin II gene.

Jost J, Seldran M, Geiser M Proc Natl Acad Sci U S A. 1984; 81(2):429-33.

PMID: 6582498 PMC: 344690. DOI: 10.1073/pnas.81.2.429.

Sequence homologies in the region preceding the transcription initiation site of the liver estrogen-responsive vitellogenin and apo-VLDLII genes.

Walker P, Germond J, Brown-Luedi M, Givel F, Wahli W Nucleic Acids Res. 1984; 12(22):8611-26.

PMID: 6504705 PMC: 320402. DOI: 10.1093/nar/12.22.8611.

An estrogen-dependent demethylation at the 5' end of the chicken vitellogenin gene is independent of DNA synthesis.

Wilks A, Seldran M, Jost J Nucleic Acids Res. 1984; 12(2):1163-77.

PMID: 6198632 PMC: 318563. DOI: 10.1093/nar/12.2.1163.

Eukaryotic DNA methylation.

Cooper D Hum Genet. 1983; 64(4):315-33.

PMID: 6194100 DOI: 10.1007/BF00292363.

References

Compere S, Palmiter R . DNA methylation controls the inducibility of the mouse metallothionein-I gene lymphoid cells. Cell. 1981; 25(1):233-40. DOI: 10.1016/0092-8674(81)90248-8. View

Jentsch S, Gunthert U, Trautner T . DNA methyltransferases affecting the sequence 5'CCGG. Nucleic Acids Res. 1981; 9(12):2753-9. PMC: 326890. DOI: 10.1093/nar/9.12.2753. View

Arnberg A, Meijlink F, Mulder J, van Bruggen E, Gruber M, Geert A . Isolation and characterization of genomic clones covering the chicken vitellogenin gene. Nucleic Acids Res. 1981; 9(14):3271-86. PMC: 327351. DOI: 10.1093/nar/9.14.3271. View

Naveh-Many T, Cedar H . Active gene sequences are undermethylated. Proc Natl Acad Sci U S A. 1981; 78(7):4246-50. PMC: 319766. DOI: 10.1073/pnas.78.7.4246. View

Wilks A, Cozens P, Mattaj I, Jost J . Estrogen induces a demethylation at the 5' end region of the chicken vitellogenin gene. Proc Natl Acad Sci U S A. 1982; 79(14):4252-5. PMC: 346648. DOI: 10.1073/pnas.79.14.4252. View

SHAPIRO H, Chargaff E . Studies on the nucleotide arrangement in deoxyribonucleic acids. IV. Patterns of nucleotide sequence in the deoxyribonucleic acid of rye germ and its fractions. Biochim Biophys Acta. 1960; 39:68-82. DOI: 10.1016/0006-3002(60)90123-2. View

Grippo P, Iaccarino M, Parisi E, Scarano E . Methylation of DNA in developing sea urchin embryos. J Mol Biol. 1968; 36(2):195-208. DOI: 10.1016/0022-2836(68)90375-6. View

Vanyushin B, Mazin A, Vasilyev V, BELOZERSKY A . The content of 5-methylcytosine in animal DNA: the species and tissue specificity. Biochim Biophys Acta. 1973; 299(3):397-403. DOI: 10.1016/0005-2787(73)90264-5. View

Bergink E, Kloosterboer H, Gruber M, Ab G . Estrogen-induced phosphoprotein synthesis in roosters. Kinetics of induction. Biochim Biophys Acta. 1973; 294(1):497-506. DOI: 10.1016/0005-2787(73)90105-6. View

10.

Van den Berg J, Kooistra T, Geert A, Gruber M . Effect of estradiol on the RNA content and the activity of nucleolar RNA polymerase from rooster liver. Biochem Biophys Res Commun. 1974; 61(1):367-74. DOI: 10.1016/0006-291x(74)90576-2. View

11.

Holliday R, Pugh J . DNA modification mechanisms and gene activity during development. Science. 1975; 187(4173):226-32. View

12.

Southern E . Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol. 1975; 98(3):503-17. DOI: 10.1016/s0022-2836(75)80083-0. View

13.

Blin N, Stafford D . A general method for isolation of high molecular weight DNA from eukaryotes. Nucleic Acids Res. 1976; 3(9):2303-8. PMC: 343085. DOI: 10.1093/nar/3.9.2303. View

14.

Jeffreys A, Flavell R . A physical map of the DNA regions flanking the rabbit beta-globin gene. Cell. 1977; 12(2):429-39. DOI: 10.1016/0092-8674(77)90119-2. View

15.

Jeffreys A, Flavell R . The rabbit beta-globin gene contains a large large insert in the coding sequence. Cell. 1977; 12(4):1097-108. DOI: 10.1016/0092-8674(77)90172-6. View

16.

Bird A, Southern E . Use of restriction enzymes to study eukaryotic DNA methylation: I. The methylation pattern in ribosomal DNA from Xenopus laevis. J Mol Biol. 1978; 118(1):27-47. DOI: 10.1016/0022-2836(78)90242-5. View

17.

Bird A . Use of restriction enzymes to study eukaryotic DNA methylation: II. The symmetry of methylated sites supports semi-conservative copying of the methylation pattern. J Mol Biol. 1978; 118(1):49-60. DOI: 10.1016/0022-2836(78)90243-7. View

18.

Tabak H, Flavell R . A method for the recovery of DNA from agarose gels. Nucleic Acids Res. 1978; 5(7):2321-32. PMC: 342166. DOI: 10.1093/nar/5.7.2321. View

19.

Greene P, Heyneker H, Bolivar F, Rodriguez R, Betlach M, Covarrubias A . A general method for the purification of restriction enzymes. Nucleic Acids Res. 1978; 5(7):2373-80. PMC: 342170. DOI: 10.1093/nar/5.7.2373. View

20.

Williams D, Tseng M, ROTTMANN W . Albumin synthesis and secretion by isolated morphologically characterized avian hepatic parenchymal cells. Life Sci. 1978; 23(3):195-206. DOI: 10.1016/0024-3205(78)90306-5. View