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Sendai Virus-specific T Cell Clones II. Induction of Interferon Production by Sendai Virus-specific T Helper Cell Clones

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Journal Eur J Immunol
Date 1982 Dec 1
PMID 6297920
Citations 7
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Abstract

Interferon (IFN) was detected upon co-culture of cloned Sendai virus (SV)-specific T lymphocyte with SV-presenting syngeneic stimulator cells. The antiviral activity was defined as IFN-alpha, beta. The T cell clones, upon contact with antigen-presenting stimulator cells, stimulated adherent cells present in the stimulator cell population to secrete IFN. Induction of IFN production was independent from interleukin 2 production by the T cell clones.

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