Unique Features of Retrovirus Expression in F/St Mice

Overview

Journal J Virol

Publisher American Society for Microbiology

Date 1982 Jul 1

PMID 6286989

Citations 11

Authors

H C Morse 3rd

C A Kozak

R A Yetter

J W Hartley

Affiliations

Soon will be listed here.

Abstract

F/St mice are unique in producing high levels of both ecotropic and xenotropic murine leukemia virus. The high ecotropic virus phenotype is determined by three or more V (virus-inducing) loci. A single locus for inducibility of xenotropic murine leukemia virus was mapped to chromosome 1 close to, but possibly not allelic to, Bxv-1. Although the high ecotropic virus phenotype is phenotypically dominant, the high xenotropic virus phenotype was recessive in all crosses tested. Suppression of xenotropic murine leukemia virus is governed by a single gene which is not linked to the xenotropic V locus.

Citing Articles

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Martin C, Buckler-White A, Wollenberg K, Kozak C J Virol. 2013; 87(18):10094-104.

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Complete genome sequences of new xenotropic murine leukemia viruses from the senescence-accelerated mouse (SAM): molecular and phylogenetic analyses.

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